Access the full text.
Sign up today, get DeepDyve free for 14 days.
S. Simon, W. Liedtke (2008)
How irritating: the role of TRPA1 in sensing cigarette smoke and aerogenic oxidants in the airways.The Journal of clinical investigation, 118 7
D. Miedinger, D. Gautrin, R. Castano (2012)
Upper airway symptoms among workers with work-related respiratory complaints.Occupational medicine, 62 6
A. Vertigan, Sarah Bone, P. Gibson (2013)
Laryngeal sensory dysfunction in laryngeal hypersensitivity syndromeRespirology, 18
R. Maricle (1983)
Vocal-cord dysfunction presenting as asthma.The New England journal of medicine, 309 19
Omar Husein, T. Husein, Ricky Gardner, Tendy Chiang, Douglas Larson, Keri Obert, Jennifer Thompson, Micheal Trudeau, Don Dell, L. Forrest (2008)
Formal Psychological Testing in Patients With Paradoxical Vocal Fold DysfunctionThe Laryngoscope, 118
J. Beach, B. Rowe, S. Blitz, E. Crumley, N. Hooton, K. Russell, C. Spooner, T. Klassen (2005)
Diagnosis and management of work-related asthma.Evidence report/technology assessment, 129
M. Morrison, Linda Rammage, A. Emami (1999)
The irritable larynx syndrome.Journal of voice : official journal of the Voice Foundation, 13 3
R. Irwin, Robert Ownbey, P. Cagle, S. Baker, A. Fraire (2006)
Interpreting the histopathology of chronic cough: a prospective, controlled, comparative study.Chest, 130 2
C. Ludlow (2005)
Central nervous system control of the laryngeal muscles in humansRespiratory Physiology & Neurobiology, 147
A comprehensive review of chronic cough in workplace with differential diagnosis and management algorithm
R. Hoy, M. Ribeiro, J. Anderson, S. Tarlo (2010)
Work-associated irritable larynx syndrome.Occupational medicine, 60 7
Marlene Santos, Hyejung Jung, J. Peyrovi, W. Lou, G. Liss, S. Tarlo (2007)
Occupational asthma and work-exacerbated asthma: factors associated with time to diagnostic steps.Chest, 131 6
D. Bernstein (1997)
Allergic reactions to workplace allergens.JAMA, 278 22
R. Hoy (2012)
Work-related laryngeal syndromesCurrent Opinion in Allergy and Clinical Immunology, 12
G. Leibovitch, A. Oren, Melmed Rn, M. Brezis (1991)
[Vocal cord dysfunction mimicking bronchial asthma].Harefuah, 120 2
(2002)
Diagnosis of vocal cord dysfunction
Jackie Gartner-Schmidt, C. Rosen, Nandhakumar Radhakrishnan, B. Ferguson (2008)
Odor provocation test for laryngeal hypersensitivity.Journal of voice : official journal of the Voice Foundation, 22 3
N. Ryan, S. Birring, P. Gibson (2012)
Gabapentin for refractory chronic cough: a randomised, double-blind, placebo-controlled trialThe Lancet, 380
Loveleen Guglani, S. Atkinson, Avinash Hosanagar, L. Guglani (2014)
A Systematic Review of Psychological Interventions for Adult and Pediatric Patients with Vocal Cord DysfunctionFrontiers in Pediatrics, 2
A review article summarizing network plasticity in rhythm-generating networks such as respiration
Thach (2008)
Some aspects of clinical relevance in the maturation of respiratory control in infants.J Appl Physiol, 104
(2005)
Occupational exposure as triggers of asthma
Cathy Benninger, Jonathan Parsons, J. Mastronarde (2011)
Vocal cord dysfunction and asthmaCurrent Opinion in Pulmonary Medicine, 17
D. Shusterman (2002)
Review of the upper airway, including olfaction, as mediator of symptoms.Environmental Health Perspectives, 110
P. Dicpinigaitis, K. Rauf (1998)
The influence of gender on cough reflex sensitivity.Chest, 113 5
G. Gallivan, L. Hoffman, K. Gallivan (1996)
Episodic paroxysmal laryngospasm: voice and pulmonary function assessment and management.Journal of voice : official journal of the Voice Foundation, 10 1
G. Moscato, G. Pala, P. Cullinan, I. Folletti, R. Wijk, P. Pignatti, S. Quirce, J. Sastre, E. Toskala, O. Vandenplas, J. Walusiak‐Skorupa, J. Malo (2014)
EAACI Position Paper on assessment of cough in the workplaceAllergy, 69
M. Leiner, A. Dwivedi, M. Villanos, Namrata Singh, Dan Blunk, J. Peinado (2014)
Psychosocial Profile of Bullies, Victims, and Bully-Victims: A Cross-Sectional StudyFrontiers in Pediatrics, 2
John Perkner, K. Fennelly, R. Balkissoon, B. Bartelson, A. Ruttenber, R. Wood, L. Newman (1998)
Irritant-associated vocal cord dysfunction.Journal of occupational and environmental medicine, 40 2
A highly readable and clear review on complex mechanisms in peripheral and central plasticity
(2010)
Central mechanisms of pathologic pain
S. Tarlo, I. Broder (1991)
Outcome of assessments for occupational asthma.Chest, 100 2
J. Smith, L. Houghton (2013)
The oesophagus and cough: laryngo-pharyngeal reflux, microaspiration and vagal reflexesCough (London, England), 9
A. Vertigan, Sarah Bone, P. Gibson (2014)
Development and validation of the Newcastle laryngeal hypersensitivity questionnaireCough (London, England), 10
B. Thach (2008)
Neural Control of Perinatal Respiration Some aspects of clinical relevance in the maturation of respiratory control in infants
H. Koch, Alfredo Garcia, J. Ramirez (2011)
Network reconfiguration and neuronal plasticity in rhythm-generating networks.Integrative and comparative biology, 51 6
Paul Vigo, M. Grayson (2005)
Occupational exposures as triggers of asthma.Immunology and allergy clinics of North America, 25 1
J. Bouvier, M. Thoby-Brisson, N. Renier, V. Dubreuil, J. Ericson, J. Champagnat, A. Pierani, A. Chédotal, G. Fortin (2010)
Hindbrain interneurons and axon guidance signaling critical for breathingNature Neuroscience, 13
M. Raulf‐Heimsoth, Xaver Baur (1998)
Pathomechanisms and pathophysiology of isocyanate-induced diseases--summary of present knowledge.American journal of industrial medicine, 34 2
K. Newman, U. Mason, K. Schmaling (1995)
Clinical features of vocal cord dysfunction.American journal of respiratory and critical care medicine, 152 4 Pt 1
T. Murry, R. Branski, Kathy Yu, Sabrina Cukier-Blaj, S. Duflo, J. Aviv (2010)
Laryngeal sensory deficits in patients with chronic cough and paradoxical vocal fold movement disorderThe Laryngoscope, 120
M. Morris, K. Christopher (2010)
Diagnostic criteria for the classification of vocal cord dysfunction.Chest, 138 5
Bryant Lee, P. Woo (2005)
Chronic Cough as a Sign of Laryngeal Sensory Neuropathy: Diagnosis and TreatmentAnnals of Otology, Rhinology & Laryngology, 114
M. Andrianopoulos, G. Gallivan, K. Gallivan (2000)
PVCM, PVCD, EPL, and irritable larynx syndrome: what are we talking about and how do we treat it?Journal of voice : official journal of the Voice Foundation, 14 4
A useful validated questionnaire to diagnose and assess laryngeal hypersensitivity (underlying disease in WILS)
E. Millqvist (2008)
Mechanisms of increased airway sensitivity to occupational chemicals and odorsCurrent Opinion in Allergy and Clinical Immunology, 8
(2007)
Paradox - ical vocal cord motion disorder : past , present and future
R. Kuner (2010)
Central mechanisms of pathological painNature Medicine, 16
J. Ayres, Paul Gabbott (2002)
Are oral appliances a substitute for nasal positive airway pressure?Thorax, 57
Jon Ayres (1999)
Pseudo-steroid resistant asthmaThorax, 54
(2014)
A systematic reiew of psychological interventions for adult and pediatric patients with vocal cords dysfunction
A. Vertigan, P. Gibson, D. Theodoros, A. Winkworth (2007)
A review of voice and upper airway function in chronic cough and paradoxical vocal cord movementCurrent Opinion in Allergy and Clinical Immunology, 7
REVIEW URRENT PINION Jennifer A. Anderson Purpose of review The purpose of this study is to review the relevant literature concerning work-associated irritable larynx syndrome (WILS), a hyperkinetic laryngeal disorder associated with occupational irritant exposure. Clinical symptoms are variable and include dysphonia, cough, dyspnoea and globus pharyngeus. WILS is a clinical diagnosis and can be difficult to differentiate from asthma. Treatment options for WILS include medical and behavioural therapy. Recent findings Laryngeal-centred upper airway symptoms secondary to airborne irritants have been documented in the literature under a variety of diagnostic labels, including WILS, vocal cord dysfunction (VCD), laryngeal hypersensitivity and laryngeal neuropathy and many others. The underlying pathophysiology is as yet poorly understood; however, the clinical scenario suggests a multifactorial nature to the disorder. More recent literature indicates that central neuronal plasticity, inflammatory processes and psychological factors are all likely contributors. Summary Possible mechanisms for WILS include central neuronal network plasticity after noxious exposure and/or viral infection, inflammation (i.e. reflux disease) and intrinsic patient factors such a psychological state. Treatment is individualized and frequently includes one or more of the following: environmental changes in the workplace, GERD therapy, behavioural/speech therapy, psychotherapy counselling and neural modifiers. Keywords cough, dysphonia, irritable
Current Opinion in Allergy and Clinical Immunology – Wolters Kluwer Health
Published: Apr 1, 2015
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.