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Visual Assessment of Aqueous Humor Outflow

Visual Assessment of Aqueous Humor Outflow Downloaded from http://journals.lww.com/apjoo by BhDMf5ePHKbH4TTImqenVA5KvPVPZ0P5BEgU+IUTEfzO/GUWifn2IfwcEVVH9SSn on 06/04/2020 REVIEW ARTICLE Xiaobin Xie, MD,*† Goichi Akiyama, MD, PhD,† Thania Bogarin, MS,† Sindhu Saraswathy, PhD,† and Alex S. Huang, MD, PhD† explosion of minimally invasive glaucoma surgeries (MIGS), Abstract: In the past decade, many new pharmacological and surgical 5 6 7 most of which ablate or bypass the trabecular meshwork (TM). treatments have become available to lower intraocular pressure (IOP) for The challenge is that these treatments have adverse effects or do glaucoma. The majority of these options have targeted improving aqueous not always lower IOP, raising the question as to whether we fully humor outflow (AHO). At the same time, in addition to new treatments, understand the biology of AHO. Research spurred by this variable research advances in AHO assessment have led to the development of clinical success has now demonstrated that AHO is actually much new tools to structurally assess AHO pathways and to visualize where more complicated than originally anticipated. aqueous is flowing in the eye. These new imaging modalities have Aqueous humor outflow naturally occurs through 2 pathways, uncovered novel AHO observations that challenge traditional AHO the conventional (trabecular) and unconventional (uveoscleral) concepts. New behaviors including segmental, pulsatile, http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png The Asia-Pacific Journal of Ophthalmology Wolters Kluwer Health

Visual Assessment of Aqueous Humor Outflow

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Publisher
Wolters Kluwer Health
ISSN
2162-0989
eISSN
2475-5028
DOI
10.22608/APO.201911
Publisher site
See Article on Publisher Site

Abstract

Downloaded from http://journals.lww.com/apjoo by BhDMf5ePHKbH4TTImqenVA5KvPVPZ0P5BEgU+IUTEfzO/GUWifn2IfwcEVVH9SSn on 06/04/2020 REVIEW ARTICLE Xiaobin Xie, MD,*† Goichi Akiyama, MD, PhD,† Thania Bogarin, MS,† Sindhu Saraswathy, PhD,† and Alex S. Huang, MD, PhD† explosion of minimally invasive glaucoma surgeries (MIGS), Abstract: In the past decade, many new pharmacological and surgical 5 6 7 most of which ablate or bypass the trabecular meshwork (TM). treatments have become available to lower intraocular pressure (IOP) for The challenge is that these treatments have adverse effects or do glaucoma. The majority of these options have targeted improving aqueous not always lower IOP, raising the question as to whether we fully humor outflow (AHO). At the same time, in addition to new treatments, understand the biology of AHO. Research spurred by this variable research advances in AHO assessment have led to the development of clinical success has now demonstrated that AHO is actually much new tools to structurally assess AHO pathways and to visualize where more complicated than originally anticipated. aqueous is flowing in the eye. These new imaging modalities have Aqueous humor outflow naturally occurs through 2 pathways, uncovered novel AHO observations that challenge traditional AHO the conventional (trabecular) and unconventional (uveoscleral) concepts. New behaviors including segmental, pulsatile,

Journal

The Asia-Pacific Journal of Ophthalmology – Wolters Kluwer Health

Published: Mar 1, 2019

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