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Uptake of biomedical interventions for prevention of sexually transmitted HIV Ume L. Abbas Department of Infectious Diseases, Cleveland Clinic Purpose of the review Foundation, Cleveland, Ohio, USA To examine the population-level effects of introducing and/or expanding biomedical Correspondence to Ume L. Abbas, MD, Department of interventions for prevention of human immunodeficiency virus (HIV) sexually transmitted Infectious Diseases, Cleveland Clinic Foundation, infections through mathematical modeling. 9500 Euclid Avenue/G21, Cleveland, OH 44195, USA Tel: +1 216 636 1873; e-mail: abbasu@ccf.org Recent findings Successes of several ground-breaking clinical trials have invigorated the field of HIV Current Opinion in HIV and AIDS 2011, 6:114–118 prevention with new enthusiasm and opportunities for research into and application of biomedical HIV prevention. Mathematical modeling has advanced in tandem with valuable contributions to both investigative science and public health. New models provide qualitative and quantitative insights regarding the epidemiological impact of the uptake of biomedical interventions, singly and/or in combination including treatment of sexually transmitted infections, condom use, male circumcision, antiretroviral treatment and pre-exposure prophylaxis and vaccine for HIV prevention. Summary Biomedical interventions are critical for reversing the HIV pandemic. Mathematical modeling is invaluable for informed biomedical HIV prevention research, policy and practice. Keywords antiretroviral pre-exposure prophylaxis,
Current Opinion in HIV and Aids – Wolters Kluwer Health
Published: Mar 1, 2011
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