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"United Airways Disease" and Phenotypic Peculiarities of Respiratory Allergy in Immigrants

"United Airways Disease" and Phenotypic Peculiarities of Respiratory Allergy in Immigrants EDITORIAL ‘‘United Airways Disease’’ and Phenotypic Peculiarities of Respiratory Allergy in Immigrants Carlo Lombardi, Giovanni Passalaqua, and Giorgio Walter Canonica Abstract: Allergy is the result of a complex interaction between genetic background and environmental factors, including exposure to allergens and lifestyle. Migration is a process that involves many radical changes in the environment, including diet, pollutants, allergens, different housing conditions, and patterns of infections. Thus, studies in immigrants may provide important information about the role of environmental factors in the development of allergic respiratory diseases. Several studies addressed this aspect and consistently found that migrants develop allergies at different rates from the local population, and very often the symptoms appear with a delay of 3 to 5 years after migration. More recent data showed that the severity of allergic diseases is greater in migrants, and that usually the onset is with associated asthma and rhinitis. The immigration model strongly suggests that environmental factors overcome the genetic background, and that the clinical phenotype of respiratory allergy in migrants has some peculiarities. Key Words: asthma, rhinitis, allergy, immigration, migrants espiratory allergy (ie, rhinitis and asthma) has a high prevalence and, at least for rhinitis, Rthe prevalence is constantly increasing worldwide. Currently, http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png World Allergy Organization Journal Wolters Kluwer Health

"United Airways Disease" and Phenotypic Peculiarities of Respiratory Allergy in Immigrants

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References (32)

ISSN
1939-4551
DOI
10.1097/WOX.0b013e3181971b89
pmid
23282932
Publisher site
See Article on Publisher Site

Abstract

EDITORIAL ‘‘United Airways Disease’’ and Phenotypic Peculiarities of Respiratory Allergy in Immigrants Carlo Lombardi, Giovanni Passalaqua, and Giorgio Walter Canonica Abstract: Allergy is the result of a complex interaction between genetic background and environmental factors, including exposure to allergens and lifestyle. Migration is a process that involves many radical changes in the environment, including diet, pollutants, allergens, different housing conditions, and patterns of infections. Thus, studies in immigrants may provide important information about the role of environmental factors in the development of allergic respiratory diseases. Several studies addressed this aspect and consistently found that migrants develop allergies at different rates from the local population, and very often the symptoms appear with a delay of 3 to 5 years after migration. More recent data showed that the severity of allergic diseases is greater in migrants, and that usually the onset is with associated asthma and rhinitis. The immigration model strongly suggests that environmental factors overcome the genetic background, and that the clinical phenotype of respiratory allergy in migrants has some peculiarities. Key Words: asthma, rhinitis, allergy, immigration, migrants espiratory allergy (ie, rhinitis and asthma) has a high prevalence and, at least for rhinitis, Rthe prevalence is constantly increasing worldwide. Currently,

Journal

World Allergy Organization Journal – Wolters Kluwer Health

Published: Feb 1, 2009

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