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Joanne Yu, L. May, V. Lhoták, S. Shahrzad, S. Shirasawa, J. Weitz, B. Coomber, N. Mackman, J. Rak (2005)
Oncogenic events regulate tissue factor expression in colorectal cancer cells: implications for tumor progression and angiogenesis.Blood, 105 4
Chika Shigemori, Hideo Wada, Kouichi Matsumoto, H. Shiku, Shin Nakamura, H. Suzuki (1998)
Tissue Factor Expression and Metastatic Potential of Colorectal CancerThrombosis and Haemostasis, 80
B. Offersen, P. Pfeiffer, S. Hamilton-Dutoit, J. Overgaard (2001)
Patterns of angiogenesis in nonsmall‐cell lung carcinomaCancer, 91
A. Kakkar, N. Lemoine, M. Scully, S. Tebbutt, R. Williamson (1995)
Tissue factor expression correlates with histological grade in human pancreatic cancerBritish Journal of Surgery, 82
Ron Kerr, D. Stirling, M. Rae, Anne White, C. Ludlam (2002)
A novel method for quantitation of human von Willebrand factor messenger RNA.Thrombosis research, 106 4-5
M. Sawada, S. Miyake, Shinichi Ohdama, Osamu Matsubara, S. Masuda, K. Yakumaru, Yasuyuki Yoshizawa (1999)
Expression of tissue factor in non-small-cell lung cancers and its relationship to metastasisBritish Journal of Cancer, 79
N. Tsopanoglou, M. Maragoudakis (1999)
On the Mechanism of Thrombin-induced AngiogenesisThe Journal of Biological Chemistry, 274
Y. Oshika, M. Nakamura, T. Tokunaga, Y. Ozeki, Y. Fukushima, H. Hatanaka, Y. Abe, H. Yamazaki, H. Kijima, N. Tamaoki, Y. Ueyama (1998)
Expression of cell-associated isoform of vascular endothelial growth factor 189 and its prognostic relevance in non-small cell lung cancer.International journal of oncology, 12 3
H. Versteeg, Florence Schaffner, M. Kerver, H. Petersen, J. Ahamed, B. Felding‐Habermann, Y. Takada, B. Mueller, W. Ruf (2014)
Hemostasis, Thrombosis, and Vascular Biology: Inhibition of tissue factor signaling suppresses tumor growth
T. Yano, S. Tanikawa, T. Fujie, M. Masutani, T. Horie (2000)
Vascular endothelial growth factor expression and neovascularisation in non-small cell lung cancer.European journal of cancer, 36 5
A. Meert, M. Paesmans, B. Martin, P. Delmotte, T. Berghmans, J. Verdebout, J. Lafitte, C. Mascaux, J. Sculier (2002)
The role of microvessel density on the survival of patients with lung cancer: a systematic review of the literature with meta-analysisBritish Journal of Cancer, 87
N. Weidner, J. Semple, W. Welch, J. Folkman (1991)
Tumor angiogenesis and metastasis--correlation in invasive breast carcinoma.The New England journal of medicine, 324 1
D. Gorski, Alejandro Leal, James Goydos (2003)
Differential expression of vascular endothelial growth factor-A isoforms at different stages of melanoma progression.Journal of the American College of Surgeons, 197 3
C. Lackner, Z. Jukić, O. Tsybrovskyy, G. Jatzko, V. Wette, G. Hoefler, M. Klimpfinger, H. Denk, K. Zatloukal (2004)
Prognostic relevance of tumour-associated macrophages and von Willebrand factor-positive microvessels in colorectal cancerVirchows Archiv, 445
M. Beasley, E. Brambilla, W. Travis (2005)
The 2004 World Health Organization classification of lung tumors.Seminars in roentgenology, 40 2
Youming Zhang, You-Ming Deng, T. Luther, M. Müller, Reinhard Ziegler, R. Waldherr, D. Stern, P. Nawroth (1994)
Tissue factor controls the balance of angiogenic and antiangiogenic properties of tumor cells in mice.The Journal of clinical investigation, 94 3
B. Østerud, E. Bjørklid (2006)
Sources of tissue factor.Seminars in thrombosis and hemostasis, 32 1
Y. Tomii, H. Yamazaki, N. Sawa, Y. Ohnishi, J. Kamochi, T. Tokunaga, Y. Osamura, S. Sadahiro, H. Kijima, Y. Abe, Y. Ueyama, N. Tamaoki, Masato Nakamura (2002)
Unique properties of 189 amino acid isoform of vascular endothelial growth factor in tumorigenesis.International journal of oncology, 21 6
J. Kononen, L. Bubendorf, Anne Kallionimeni, M. Bärlund, P. Schraml, S. Leighton, J. Torhorst, M. Mihatsch, G. Sauter, Olli-P. Kallionimeni (1998)
Tissue microarrays for high-throughput molecular profiling of tumor specimensNature Medicine, 4
N. Ferrara, H. Gerber, J. Lecouter (2003)
The biology of VEGF and its receptorsNature Medicine, 9
R. White, H. Chew, Hong Zhou, A. Parikh-Patel, D. Harris, D. Harvey, T. Wun (2005)
Incidence of venous thromboembolism in the year before the diagnosis of cancer in 528,693 adults.Archives of internal medicine, 165 15
M. Koukourakis, A. Giatromanolaki, P. Thorpe, R. Brekken, E. Sivridis, S. Kakolyris, V. Georgoulias, K. Gatter, A. Harris (2000)
Vascular endothelial growth factor/KDR activated microvessel density versus CD31 standard microvessel density in non-small cell lung cancer.Cancer research, 60 11
M. Hervé, Hélène Buteau-Lozano, R. Vassy, I. Bièche, Guillaume Velasco, M. Pla, G. Perret, S. Mourah, M. Perrot-Applanat (2008)
Overexpression of vascular endothelial growth factor 189 in breast cancer cells leads to delayed tumor uptake with dilated intratumoral vessels.The American journal of pathology, 172 1
Versteeg (2008)
Inhibition of tissue factor signaling suppresses tumor growthBlood, 111
O. Adighibe, K. Micklem, L. Campo, M. Ferguson, A. Harris, R. Pozos, K. Gatter, F. Pezzella (2006)
Is nonangiogenesis a novel pathway for cancer progression? A study using 3-dimensional tumour reconstructionsBritish Journal of Cancer, 94
J. Bazan (1990)
Structural design and molecular evolution of a cytokine receptor superfamily.Proceedings of the National Academy of Sciences of the United States of America, 87
M. Belting, Michael Dorrell, Staffan Sandgren, E. Aguilar, J. Ahamed, Andrea Dorfleutner, P. Carmeliet, B. Mueller, M. Friedlander, W. Ruf (2004)
Regulation of angiogenesis by tissue factor cytoplasmic domain signalingNature Medicine, 10
A. Khorana, S. Ahrendt, C. Ryan, C. Francis, R. Hruban, Yingchuan Hu, G. Hostetter, Jennifer Harvey, M. Taubman (2007)
Tissue Factor Expression, Angiogenesis, and Thrombosis in Pancreatic CancerClinical Cancer Research, 13
D. Hicklin, L. Ellis (2005)
Role of the vascular endothelial growth factor pathway in tumor growth and angiogenesis.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 23 5
Kan-kan Wang, Ni Liu, N. Radulovich, D. Wigle, M. Johnston, F. Shepherd, M. Minden, M. Tsao (2002)
Novel candidate tumor marker genes for lung adenocarcinomaOncogene, 21
F. Pezzella, U. Pastorino, E. Tagliabue, S. Andreola, G. Sozzi, G. Gasparini, S. Ménard, K. Gatter, A. Harris, Steve Fox, M. Buyse, S. Pilotti, M. Pierotti, F. Rilke (1997)
Non-small-cell lung carcinoma tumor growth without morphological evidence of neo-angiogenesis.The American journal of pathology, 151 5
T. Urban, S. Ricci, C. Danel, M. Antoine, M. Kambouchner, V. Godard, R. Lacave, J. Bernaudin (2000)
Detection of codon 12 K- ras mutations in non-neoplastic mucosa from bronchial carina in patients with lung adenocarcinomasBritish Journal of Cancer, 82
M. Belting, J. Ahamed, W. Ruf (2005)
Signaling of the Tissue Factor Coagulation Pathway in Angiogenesis and CancerArteriosclerosis, Thrombosis, and Vascular Biology, 25
N. Weidner, Peter Carroll, Jonathan, Flax, W. Blumenfeld, J. Folkman (1993)
Tumor angiogenesis correlates with metastasis in invasive prostate carcinoma.The American journal of pathology, 143 2
F. Rickles, M. Levine (2001)
Epidemiology of Thrombosis in CancerActa Haematologica, 106
N. Tsopanoglou, M. Maragoudakis (2004)
Role of thrombin in angiogenesis and tumor progression.Seminars in thrombosis and hemostasis, 30 1
J. Rollin, S. Iochmann, C. Bléchet, F. Hubé, S. Régina, S. Guyétant, E. Lemarié, P. Reverdiau, Y. Gruel (2005)
Expression and methylation status of tissue factor pathway inhibitor-2 gene in non-small-cell lung cancerBritish Journal of Cancer, 92
A. Eberhard, S. Kahlert, Valentin Goede, B. Hemmerlein, K. Plate, H. Augustin (2000)
Heterogeneity of angiogenesis and blood vessel maturation in human tumors: implications for antiangiogenic tumor therapies.Cancer research, 60 5
M. Bromberg, R. Sundaram, R. Homer, A. Garen, William Konigsberg (1999)
Role of Tissue Factor in Metastasis: Functions of the Cytoplasmic and Extracellular Domains of the MoleculeThrombosis and Haemostasis, 82
L. Hlatky, P. Hahnfeldt, J. Folkman (2002)
Clinical application of antiangiogenic therapy: microvessel density, what it does and doesn't tell us.Journal of the National Cancer Institute, 94 12
L. Sobin, M. Gospodarowicz, C. Wittekind (2010)
Lung and Pleural Tumours
K. Abe, M. Shoji, Jiang Chen, A. Bierhaus, I. Danave, Cornelia Micko, K. Casper, D. Dillehay, P. Nawroth, F. Rickles (1999)
Regulation of vascular endothelial growth factor production and angiogenesis by the cytoplasmic tail of tissue factor.Proceedings of the National Academy of Sciences of the United States of America, 96 15
P. Reverdiau, A. Jarousseau, G. Thibault, B. Khalfoun, H. Watier, Y. Lebranchu, P. Bardos, Y. Gruel (1995)
Tissue Factor Activity of Syncytiotrophoblast Plasma Membranes and Tumoral Trophoblast Cells in CultureThrombosis and Haemostasis, 73
Richards Ge, Johnson Be (1993)
The biology of lung cancer.Seminars in oncology, 20 2
V. Ollivier, S. Bentolila, J. Chabbat, J. Hakim, D. Prost (1998)
Tissue factor-dependent vascular endothelial growth factor production by human fibroblasts in response to activated factor VII.Blood, 91 8
Takayuki Ueno, Masakazu Toi, Morio Koike, Shin Nakamura, Takeshi Tominaga (2000)
Tissue factor expression in breast cancer tissues: its correlation with prognosis and plasma concentrationBritish Journal of Cancer, 83
D. Mechtcheriakova, Alexander Wlachos, H. Holzmüller, B. Binder, E. Hofer (1999)
Vascular endothelial cell growth factor-induced tissue factor expression in endothelial cells is mediated by EGR-1.Blood, 93 11
M. Monte, H. Nonnenmacher, N. Brignon, M. Ullmann, Jean‐Pierre Martin (2002)
A multivariate statistical analysis to follow the course of disease after infection of cats with different strains of the feline immunodeficiency virus (FIV).Journal of virological methods, 103 2
R. Koomägi, M. Volm (1998)
Tissue‐factor expression in human non‐small‐cell lung carcinoma measured by immunohistochemistry: Correlation between tissue factor and angiogenesisInternational Journal of Cancer, 79
J. Rak, P. Klement, J. Yu (2006)
Genetic determinants of cancer coagulopathy, angiogenesis and disease progression.Vnitrni lekarstvi, 52 Suppl 1
R. Slebos, R. Kibbelaar, O. Dalesio, A. Kooistra, Jacob Stam, C. Meijer, S. Wagenaar, R. Vanderschueren, N. Zandwijk, W. Mooi, J. Bos, S. Rodenhuis (1990)
K-ras oncogene activation as a prognostic marker in adenocarcinoma of the lung.The New England journal of medicine, 323 9
Rolf Stahel (1994)
Biology of lung cancer.Lung cancer, 10 Suppl 1
P. Cirillo, S. Rosa, M. Pacileo, A. Gargiulo, Antonio Leonardi, V. Angri, Silvestro Formisano, Massimo Chiariello (2006)
Nicotine induces tissue factor expression in cultured endothelial and smooth muscle cellsJournal of Thrombosis and Haemostasis, 4
T. Keller, U. Salge, H. König, J. Dodt, Marina Heiden, R. Seitz (2001)
Tissue factor is the only activator of coagulation in cultured human lung cancer cells.Lung cancer, 31 2-3
ORIGINAL ARTICLE Tissue Factor Expression in Non-small Cell Lung Cancer: Relationship with Vascular Endothelial Growth Factor Expression, Microvascular Density, and K-ras Mutation Sandra Regina, MD,*†‡ Je´roˆme Rollin, PhD,†‡ Claire Ble´chet, MD,†‡§ Sophie Iochmann, PhD,*†‡ Pascale Reverdiau, PhD,*†‡ and Yves Gruel, MD*†‡ Several normal cells such as fibroblasts in the adventitia of Introduction: Tissue factor (TF) is the physiological trigger of blood vessels constitutively express TF, but cytokines, blood coagulation, but it could also have an important role in cancer growth factors, and endotoxins can also promote TF gene by regulating VEGF expression and angiogenesis. expression in vascular endothelial cells and circulating mono- Methods: TF expression was studied by real-time PCR in lung cytes. TF has also been recognized as having a key role in tumors of 64 patients with non-small-cell lung cancer (NSCLC) and certain cancers, particularly by regulating vascular endothelial by immunohistochemical analysis. The gene expression of two 3,4 growth factor (VEGF) expression and tumor angiogenesis. It is VEGF isoforms, VEGF and VEGF , was also evaluated. Mi- 165 189 5 now well established that certain tumor cells such as breast, crovascular density (MVD) was studied by measuring Von Wille- glioma, and pancreatic cancer cells express TF at
Journal of Thoracic Oncology – Wolters Kluwer Health
Published: Jul 1, 2008
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