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The role of IL-17, IL-23 and IL-31, IL-33 in allergic skin diseases

The role of IL-17, IL-23 and IL-31, IL-33 in allergic skin diseases Downloaded from http://journals.lww.com/co-allergy by BhDMf5ePHKbH4TTImqenVJ2toCr/9wZZjwPUWvYES9l2nY+zyylnl33NGMK6MRsx on 10/02/2020 REVIEW URRENT The role of IL-17, IL-23 and IL-31, IL-33 in allergic PINION skin diseases a a b c Fatih A. Topal , Torsten Zuberbier , Michael P. Makris , and Maja Hofmann Purpose of review Allergic skin diseases such as urticaria, atopic dermatitis and allergic contact dermatitis are among the most common skin diseases with severe socioeconomic consequences. The pathogenesis of allergic skin diseases is complex. This review provides an overview of cytocines IL-17, IL-23, IL-31 and IL-33. Recent findings Current research results show a variety of immunological processes in the pathogenesis of the allergic skin diseases, including the role of cytokines. In addition to the Th1 and Th2 immune response, the immune response via Th17 is becoming increasingly important in allergic skin diseases but also the cytokines IL-23, IL-31 and IL-33 have been discussed in the literature recently. Different cytokines promote in a kind of orchestra the different symptoms seen in the different allergic skin diseases, including pruritus, dermatitis, mast cell mediator release and inflammation. Summary We are still in the early stages of understanding pathophysiology of allergic skin diseases and the role of various cytokines in the immune system. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Current Opinion in Allergy & Clinical Immunology Wolters Kluwer Health

The role of IL-17, IL-23 and IL-31, IL-33 in allergic skin diseases

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Publisher
Wolters Kluwer Health
Copyright
Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.
ISSN
1528-4050
eISSN
1473-6322
DOI
10.1097/ACI.0000000000000658
Publisher site
See Article on Publisher Site

Abstract

Downloaded from http://journals.lww.com/co-allergy by BhDMf5ePHKbH4TTImqenVJ2toCr/9wZZjwPUWvYES9l2nY+zyylnl33NGMK6MRsx on 10/02/2020 REVIEW URRENT The role of IL-17, IL-23 and IL-31, IL-33 in allergic PINION skin diseases a a b c Fatih A. Topal , Torsten Zuberbier , Michael P. Makris , and Maja Hofmann Purpose of review Allergic skin diseases such as urticaria, atopic dermatitis and allergic contact dermatitis are among the most common skin diseases with severe socioeconomic consequences. The pathogenesis of allergic skin diseases is complex. This review provides an overview of cytocines IL-17, IL-23, IL-31 and IL-33. Recent findings Current research results show a variety of immunological processes in the pathogenesis of the allergic skin diseases, including the role of cytokines. In addition to the Th1 and Th2 immune response, the immune response via Th17 is becoming increasingly important in allergic skin diseases but also the cytokines IL-23, IL-31 and IL-33 have been discussed in the literature recently. Different cytokines promote in a kind of orchestra the different symptoms seen in the different allergic skin diseases, including pruritus, dermatitis, mast cell mediator release and inflammation. Summary We are still in the early stages of understanding pathophysiology of allergic skin diseases and the role of various cytokines in the immune system.

Journal

Current Opinion in Allergy & Clinical Immunology – Wolters Kluwer Health

Published: Aug 1, 2020

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