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The role of fungi in the airway of chronic rhinosinusitis patients

The role of fungi in the airway of chronic rhinosinusitis patients a b Ahmed Ragab and Peter Clement Purpose of review Introduction To analyze the role of fungi in the upper and lower airway in Chronic rhinosinusitis (CRS) is one of the most common chronic rhinosinusitis patients. long-term illnesses in the world. It affects approximately Recent findings 15% of the adult population in western countries [1]. The Recently, the involvement of the lower airway (as asthma, disorder has also been demonstrated to cause significant small airway disease and bronchial hyperresponsiveness) in physical symptoms that negatively affect quality of life chronic rhinosinusitis patients had been documented. [2]. In addition, CRS is also a significant health problem Fungal spores after inhalation are submerged in the that results in a large financial burden on societies [3]. aqueous lining layers of the airway. The site depends on the When associated with other comorbidities such as lower size of the inhaled spores. The process of inhalation, airway diseases, an increased burden on the individual retention and clearance of fungal spores may explain the and community levels is anticipated [4]. positive culture results in both normal subjects and in most chronic rhinosinusitis patients. Fungal culture of different The etiology of CRS with or without nasal polyps http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Current Opinion in Allergy and Clinical Immunology Wolters Kluwer Health

The role of fungi in the airway of chronic rhinosinusitis patients

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References (66)

ISSN
1528-4050
eISSN
1473-6322
DOI
10.1097/ACI.0b013e328013c84c
pmid
17218806
Publisher site
See Article on Publisher Site

Abstract

a b Ahmed Ragab and Peter Clement Purpose of review Introduction To analyze the role of fungi in the upper and lower airway in Chronic rhinosinusitis (CRS) is one of the most common chronic rhinosinusitis patients. long-term illnesses in the world. It affects approximately Recent findings 15% of the adult population in western countries [1]. The Recently, the involvement of the lower airway (as asthma, disorder has also been demonstrated to cause significant small airway disease and bronchial hyperresponsiveness) in physical symptoms that negatively affect quality of life chronic rhinosinusitis patients had been documented. [2]. In addition, CRS is also a significant health problem Fungal spores after inhalation are submerged in the that results in a large financial burden on societies [3]. aqueous lining layers of the airway. The site depends on the When associated with other comorbidities such as lower size of the inhaled spores. The process of inhalation, airway diseases, an increased burden on the individual retention and clearance of fungal spores may explain the and community levels is anticipated [4]. positive culture results in both normal subjects and in most chronic rhinosinusitis patients. Fungal culture of different The etiology of CRS with or without nasal polyps

Journal

Current Opinion in Allergy and Clinical ImmunologyWolters Kluwer Health

Published: Feb 1, 2007

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