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ORIGINAL ARTICLE The Prognostic Value of Vascular Diameter Measurements on Routine Chest Computed Tomography in Patients Not Referred for Cardiovascular Indications Martijn J.A. Gondrie, MD, PhD,*Þ Yolanda van der Graaf, MD, PhD,* Peter C. Jacobs, MD,*Þ Stan C.F.M. Buckens, MD,* and Willem P.Th.M. Mali, MD, PhDÞ and On Behalf of the PROVIDI Study Group from more unrequested findings being detected, the increased Objectives: The aim of the study was to investigate whether diameter image quality results in opportunities for more accurate mea- measurements of the thoracic aorta and the heart can be used as prog- surements in routine scanning. The investigation of the clinical nostic markers for future cardiovascular disease. value of such easy-to-measure image findings on routine daily Methods: Following a case-cohort design, a total of 10,410 patients scanning could supplement the ongoing investigation of valu- undergoing chest computed tomography were followed up for a mean 3,4 able unrequested imaging findings. period of 17 months. The ones with a cardiovascular indication were ex- Simple diameter measurements of the thoracic aorta or the cluded. Diameter measurements were evaluated with Cox proportional heart and measurement of the cardiothoracic ratio (CTR), which hazard analysis. is the ratio between the heart size
Journal of Computer Assisted Tomography – Wolters Kluwer Health
Published: Nov 1, 2011
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