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The Prognostic Value of Rb-82 Positron Emission Tomography in Patients Following Heart Transplant

The Prognostic Value of Rb-82 Positron Emission Tomography in Patients Following Heart Transplant Background—Cardiac Allograft Vasculopathy (CAV) is a key prognostic determinant following heart transplant (HT). Detection and risk stratification of patients with CAV is problematic. Positron emission tomography (PET) using Rubidium-82 (Rb-82) allows quantification of absolute myocardial blood flow and may have utility for risk stratification in this population. Methods and Results—Patients with a history of HT undergoing dipyridamole Rb-82 PET were prospectively enrolled. Myocardial perfusion and left ventricular ejection fraction (LVEF) were recorded. Absolute flow quantification at rest and foll f f f f f f fol ol ol ol ol ol ollo lo lo lo lo lo o ow wi wi wi wi wi wi wi ing dipyridam ng ng ng ng ng ng ng d d d d d d dip ip ip ip ip ip ipyr yr yr yr yr yr yri i i i i i i ole stress as well as the ratio of mean glo g g bal flow at stress and at rest, st,y ,y te te e e e e er rm rm rm rm rm rm rm med ed ed ed ed ed ed ed My M M M M M M Myo yo yo yo yo yo yo oc c http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Circulation: Cardiovascular Imaging Wolters Kluwer Health

The Prognostic Value of Rb-82 Positron Emission Tomography in Patients Following Heart Transplant

Chow, Benjamin J.W.
Circulation: Cardiovascular Imaging , Volume Publish Ahead of Print – Sep 1, 2014
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References (33)

Copyright
© 2014 American Heart Association, Inc.
ISSN
1941-9651
eISSN
1942-0080
DOI
10.1161/CIRCIMAGING.114.002184
pmid
25182366
Publisher site
See Article on Publisher Site

Abstract

Background—Cardiac Allograft Vasculopathy (CAV) is a key prognostic determinant following heart transplant (HT). Detection and risk stratification of patients with CAV is problematic. Positron emission tomography (PET) using Rubidium-82 (Rb-82) allows quantification of absolute myocardial blood flow and may have utility for risk stratification in this population. Methods and Results—Patients with a history of HT undergoing dipyridamole Rb-82 PET were prospectively enrolled. Myocardial perfusion and left ventricular ejection fraction (LVEF) were recorded. Absolute flow quantification at rest and foll f f f f f f fol ol ol ol ol ol ollo lo lo lo lo lo o ow wi wi wi wi wi wi wi ing dipyridam ng ng ng ng ng ng ng d d d d d d dip ip ip ip ip ip ipyr yr yr yr yr yr yri i i i i i i ole stress as well as the ratio of mean glo g g bal flow at stress and at rest, st,y ,y te te e e e e er rm rm rm rm rm rm rm med ed ed ed ed ed ed ed My M M M M M M Myo yo yo yo yo yo yo oc c

Journal

Circulation: Cardiovascular Imaging – Wolters Kluwer Health

Published: Sep 1, 2014

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