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Massimo Puoti, Daniela Manno, Paola Nasta and Giampiero Carosi Purpose of review Introduction Persons with HIV are frequently coinfected with hepatitis C As a result of common routes of transmission, at least one- virus. We review recent data on the epidemiology and third of HIV-infected patients from Europe, Australia natural history of hepatitis C in HIV-infected persons. and USA are suffering from concomitant hepatitis C virus Recent findings (HCV) coinfection [1]. The course of HCV-associated One-quarter of persons with HIV in Europe and the USA liver disease is accelerated by HIV coinfection, but in also have hepatitis C, but its prevalence in other areas is contrast the course of HIV coinfection does not seem to under 10%. Outbreaks of acute hepatitis C among men be altered by hepatitis coinfection [2]. Introduction of having sex with men have been described in Europe. highly active antiretroviral therapy (HAART) has Hepatitis C is the cause of more than three-quarters of liver- resulted in a dramatic decline in HIV-related morbidity related deaths in HIV-seropositive individuals; however, and mortality. Thus, since the late 1990s, liver disease has liver-related morbidity and mortality are declining or stable in emerged as an important cause of death mostly
Current Opinion in HIV and Aids – Wolters Kluwer Health
Published: Nov 1, 2007
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