Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

The adverse effects of nitrous oxide

The adverse effects of nitrous oxide April 2014 No. 285 Founded in 1966 by Professor D M Davies, FRCP, FRCP Ed ISSN 0044–6394 Relatively high concentrations of N O are needed to induce anaesthesia. When the proportion of N O in a mixture with air or a b c Robin E. Ferner , Angus A. Mackenzie & Jeffrey K. Aronson oxygen causes absolute oxygen depletion a b West Midlands Centre for Adverse Drug Reactions, Department of Anaesthesia and (i.e. an inspired oxygen fraction substan- Critical Care, Birmingham, UK and Green-Templeton College, Oxford, UK tially below 0.21), the patient can suffer Correspondence to Robin E. Ferner, MSc, MD, FRCP, City Hospital, Birmingham, B18 irreversible neurological damage, with 7QH, UK. unconsciousness, convulsion and death. Tel: +44 (0)121 507 5672; e-mail: r.e.ferner@bham.ac.uk Stewart reported the case of a 12-year- old schoolgirl who stopped breathing after 42 min of N O and oxygen anaesthesia, and later died. He also noted 26 other cases. Summary Nowadays, anaesthetists using N O supple- Nitrous oxide (N O) has been used as an anaesthetic agent since 1844. It has two 2 ment it with another volatile anaesthetic to well recognized adverse effects: it oxidizes Co(I) to Co(II) and so inactivates overcome the low http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Adverse Drug Reaction Bulletin Wolters Kluwer Health

The adverse effects of nitrous oxide

Aronson, Jeffrey K.
Adverse Drug Reaction Bulletin , Volume 285 (1) – Apr 1, 2014
Download PDF
4 pages

Loading next page...
 
/lp/wolters-kluwer-health/the-adverse-effects-of-nitrous-oxide-G3Qfc0wSKv

References

References for this paper are not available at this time. We will be adding them shortly, thank you for your patience.

Copyright
© 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins
ISSN
0044-6394
eISSN
2159-7774
DOI
10.1097/FAD.0000000000000003
Publisher site
See Article on Publisher Site

Abstract

April 2014 No. 285 Founded in 1966 by Professor D M Davies, FRCP, FRCP Ed ISSN 0044–6394 Relatively high concentrations of N O are needed to induce anaesthesia. When the proportion of N O in a mixture with air or a b c Robin E. Ferner , Angus A. Mackenzie & Jeffrey K. Aronson oxygen causes absolute oxygen depletion a b West Midlands Centre for Adverse Drug Reactions, Department of Anaesthesia and (i.e. an inspired oxygen fraction substan- Critical Care, Birmingham, UK and Green-Templeton College, Oxford, UK tially below 0.21), the patient can suffer Correspondence to Robin E. Ferner, MSc, MD, FRCP, City Hospital, Birmingham, B18 irreversible neurological damage, with 7QH, UK. unconsciousness, convulsion and death. Tel: +44 (0)121 507 5672; e-mail: r.e.ferner@bham.ac.uk Stewart reported the case of a 12-year- old schoolgirl who stopped breathing after 42 min of N O and oxygen anaesthesia, and later died. He also noted 26 other cases. Summary Nowadays, anaesthetists using N O supple- Nitrous oxide (N O) has been used as an anaesthetic agent since 1844. It has two 2 ment it with another volatile anaesthetic to well recognized adverse effects: it oxidizes Co(I) to Co(II) and so inactivates overcome the low

Journal

Adverse Drug Reaction Bulletin – Wolters Kluwer Health

Published: Apr 1, 2014

There are no references for this article.