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ORIGINAL ARTICLE Survival Benefits from Follow-Up of Patients with Lung Cancer A Systematic Review and Meta-Analysis Lynn Calman, PhD,* Kinta Beaver, PhD,† Daniel Hind, PhD,‡ Paul Lorigan, MB,§ Chris Roberts, PhD, and Myfanwy Lloyd-Jones, DPhil¶ low-up strategies. More robust data, in the form of randomized Introduction: The burden of lung cancer is high for patients and controlled trials, are needed to confirm these findings as the review carers. Care after treatment may have the potential to impact on this. is based primarily on observational studies. Future research We reviewed the published literature on follow-up strategies in- should also include patient-centered outcomes to investigate the tended to improve survival and quality of life. impact of follow-up regimes on living with lung cancer and Methods: We systematically reviewed studies comparing follow-up psychosocial well-being. regimes in lung cancer. Primary outcomes were overall survival (comparing more intensive versus less intensive follow-up) and Key Words: Lung cancer, Follow-up, Aftercare, Survival, survival comparing symptomatic with asymptomatic recurrence. Survivorship. Quality of life was identified as a secondary outcome measure. (J Thorac Oncol. 2011;6: 1993–2004) Hazard ratios (HRs) and 95% confidence intervals from eligible studies were synthesized. Results: Nine studies that examined the role of more intensive
Journal of Thoracic Oncology – Wolters Kluwer Health
Published: Dec 1, 2011
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