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Study of the possible cardioprotective effects of insulin, ATP, and L-arginine against isoproterenol-induced myocardial infarction

Study of the possible cardioprotective effects of insulin, ATP, and L-arginine against... 12 Original article Study of the possible cardioprotective effects of insulin, ATP, and L-arginine against isoproterenol-induced myocardial infarction Fatma A. Mohamed, Mona A. Ahmed, Enas A. Abdel-Hady, Mohamed F. Abdel-Salam and Mahmoud H. Ayobe Department of Physiology, Faculty of Medicine, Background/Aim Ain Shams University, Cairo, Egypt Acute myocardial infarction remains a leading cause of morbidity and mortality Correspondence to Mona A. Ahmed, MD, Department worldwide. The present study was carried out to investigate the possible protective of Physiology, Faculty of Medicine, Ain Shams effects of insulin, ATP, and L-arginine on cardiac dysfunction in experimental University, 74 Abbassiya Street, Abdou Pasha Square, 11517 Cairo, Egypt isoproterenol (ISO)-induced myocardial infarction (MI), aiming at achieving useful Tel: + 20 224 824 860; means for protection and therapy against MI. fax: + 20 224 821 894/ + 20 226 834 576; e-mail: ahlcairo2000@yahoo.com Materials and methods Wistar rats of both sexes were allocated into five groups: the control group, the Received 26 February 2013 Accepted 18 March 2013 untreated MI group, and MI groups treated with insulin, ATP, or L-arginine. All rats were subjected to ECG recording, and plasma levels of troponin I and triglycerides were Journal of the Arab Society for Medical http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of the Arab Society for Medical Research Wolters Kluwer Health

Study of the possible cardioprotective effects of insulin, ATP, and L-arginine against isoproterenol-induced myocardial infarction

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Copyright
© 2013 The Arab Society for Medical Research
ISSN
1687-4293
DOI
10.7123/01.JASMR.0000429091.55545.fa
Publisher site
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Abstract

12 Original article Study of the possible cardioprotective effects of insulin, ATP, and L-arginine against isoproterenol-induced myocardial infarction Fatma A. Mohamed, Mona A. Ahmed, Enas A. Abdel-Hady, Mohamed F. Abdel-Salam and Mahmoud H. Ayobe Department of Physiology, Faculty of Medicine, Background/Aim Ain Shams University, Cairo, Egypt Acute myocardial infarction remains a leading cause of morbidity and mortality Correspondence to Mona A. Ahmed, MD, Department worldwide. The present study was carried out to investigate the possible protective of Physiology, Faculty of Medicine, Ain Shams effects of insulin, ATP, and L-arginine on cardiac dysfunction in experimental University, 74 Abbassiya Street, Abdou Pasha Square, 11517 Cairo, Egypt isoproterenol (ISO)-induced myocardial infarction (MI), aiming at achieving useful Tel: + 20 224 824 860; means for protection and therapy against MI. fax: + 20 224 821 894/ + 20 226 834 576; e-mail: ahlcairo2000@yahoo.com Materials and methods Wistar rats of both sexes were allocated into five groups: the control group, the Received 26 February 2013 Accepted 18 March 2013 untreated MI group, and MI groups treated with insulin, ATP, or L-arginine. All rats were subjected to ECG recording, and plasma levels of troponin I and triglycerides were Journal of the Arab Society for Medical

Journal

Journal of the Arab Society for Medical Research – Wolters Kluwer Health

Published: Jun 1, 2013

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