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Soft-tissue Hemangioblastoma of the Retroperitoneum A Case Study and Review of the Literature

Soft-tissue Hemangioblastoma of the Retroperitoneum A Case Study and Review of the Literature CASE REPORT Soft-tissue Hemangioblastoma of the Retroperitoneum A Case Study and Review of the Literature Akihiko Yoshida, MD,*w Rie Oda, MD,* Junji Shibahara, MD, PhD,w Masashi Fukayama, MD, PhD,w and Hitoshi Tsuda, MD, PhD* have also been documented. HB arising in soft tissues is 3–9 Abstract: A 71-year-old woman was found to have a solid rare, and less than 10 such cases have been reported. retroperitoneal mass measuring 7  6 cm on a computed Herein, we describe a HB occurring in the retroperitoneal tomography scan. The tumor was not connected to the spinal soft tissue of a patient without VHL, and we present a cord or large nerves. It was resected and showed the typical review of literature to better delineate the clinicopatho- histology of hemangioblastoma, that is, numerous capillaries logic characteristics of this type of tumor. and stromal cells with focal cytoplasmic vacuolization. Im- munohistochemical study revealed that the tumor stromal cells CLINICAL SUMMARY were positive for S-100 protein, neuron-specific enolase, and A retroperitoneal mass was found in a 71-year-old inhibin-a, supporting the diagnosis. In addition, the tumor cells woman during a radiologic work-up after recent surgery labeled for carbonic anhydrase IX and brachyury. The diffuse for http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Applied Immunohistochemistry & Molecular Morphology Wolters Kluwer Health

Soft-tissue Hemangioblastoma of the Retroperitoneum A Case Study and Review of the Literature

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1541-2016

Abstract

CASE REPORT Soft-tissue Hemangioblastoma of the Retroperitoneum A Case Study and Review of the Literature Akihiko Yoshida, MD,*w Rie Oda, MD,* Junji Shibahara, MD, PhD,w Masashi Fukayama, MD, PhD,w and Hitoshi Tsuda, MD, PhD* have also been documented. HB arising in soft tissues is 3–9 Abstract: A 71-year-old woman was found to have a solid rare, and less than 10 such cases have been reported. retroperitoneal mass measuring 7  6 cm on a computed Herein, we describe a HB occurring in the retroperitoneal tomography scan. The tumor was not connected to the spinal soft tissue of a patient without VHL, and we present a cord or large nerves. It was resected and showed the typical review of literature to better delineate the clinicopatho- histology of hemangioblastoma, that is, numerous capillaries logic characteristics of this type of tumor. and stromal cells with focal cytoplasmic vacuolization. Im- munohistochemical study revealed that the tumor stromal cells CLINICAL SUMMARY were positive for S-100 protein, neuron-specific enolase, and A retroperitoneal mass was found in a 71-year-old inhibin-a, supporting the diagnosis. In addition, the tumor cells woman during a radiologic work-up after recent surgery labeled for carbonic anhydrase IX and brachyury. The diffuse for

Journal

Applied Immunohistochemistry & Molecular Morphology – Wolters Kluwer Health

Published: Oct 1, 2010

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