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Role of Postoperative Radiotherapy in Nonlocalized Thymoma Propensity-Matched Analysis of Surveillance, Epidemiology, and End Results Database

Role of Postoperative Radiotherapy in Nonlocalized Thymoma Propensity-Matched Analysis of... ORIgINAL ARTICLE Role of Postoperative Radiotherapy in  Nonlocalized Thymoma Propensity-Matched Analysis of Surveillance, Epidemiology, and End Results Database Yu Jin Lim, MD,* Hak Jae Kim, MD, PhD,* and Hong-Gyun Wu, MD, PhD,*†‡ hymomas are a common primary malignancy in the Introduction: Because of a lack of randomized trials, the role of Tanterior mediastinum. According to a nation-wide postoperative radiotherapy (PORT) in thymomas has not been estab- report, the incidence of thymoma is approximately 0.15 lished. This study evaluated the prognostic impact of the adjuvant per 100,000 person-years in the United States. Although treatment in surgically resected nonlocalized thymomas. the diagnosis and histologic features of thymomas and thy- Methods: Patients diagnosed between 2000 and 2010 were identi- mic carcinomas were previously confused, their differen- fied from the Surveillance, Epidemiology, and End Results database tial schema were published in 1999 by the World Health (1973–2011 registry). Cases with localized or organ-confined tumors Organization (WHO) Consensus Committee. Masaoka were not included. Propensity-matched analysis was conducted con- staging was defined based on the primary tumor extension sidering baseline characteristics. and the degree of involvement of the surrounding organs. Results: A total of 529 patients were identified. The median age was 57 The classification of stages I to IV http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Thoracic Oncology Wolters Kluwer Health

Role of Postoperative Radiotherapy in Nonlocalized Thymoma Propensity-Matched Analysis of Surveillance, Epidemiology, and End Results Database

Wu, Hong-Gyun
Journal of Thoracic Oncology , Volume 10 (9) – Sep 1, 2015
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Copyright
Copyright © 2015 by the International Association for the Study of Lung Cancer
ISSN
1556-0864
eISSN
1556-1380
DOI
10.1097/JTO.0000000000000619
pmid
26280586
Publisher site
See Article on Publisher Site

Abstract

ORIgINAL ARTICLE Role of Postoperative Radiotherapy in  Nonlocalized Thymoma Propensity-Matched Analysis of Surveillance, Epidemiology, and End Results Database Yu Jin Lim, MD,* Hak Jae Kim, MD, PhD,* and Hong-Gyun Wu, MD, PhD,*†‡ hymomas are a common primary malignancy in the Introduction: Because of a lack of randomized trials, the role of Tanterior mediastinum. According to a nation-wide postoperative radiotherapy (PORT) in thymomas has not been estab- report, the incidence of thymoma is approximately 0.15 lished. This study evaluated the prognostic impact of the adjuvant per 100,000 person-years in the United States. Although treatment in surgically resected nonlocalized thymomas. the diagnosis and histologic features of thymomas and thy- Methods: Patients diagnosed between 2000 and 2010 were identi- mic carcinomas were previously confused, their differen- fied from the Surveillance, Epidemiology, and End Results database tial schema were published in 1999 by the World Health (1973–2011 registry). Cases with localized or organ-confined tumors Organization (WHO) Consensus Committee. Masaoka were not included. Propensity-matched analysis was conducted con- staging was defined based on the primary tumor extension sidering baseline characteristics. and the degree of involvement of the surrounding organs. Results: A total of 529 patients were identified. The median age was 57 The classification of stages I to IV

Journal

Journal of Thoracic Oncology – Wolters Kluwer Health

Published: Sep 1, 2015

References

  • Thymoma: state of the art
    Thomas
  • Malignant thymoma in the United States: demographic patterns in incidence and associations with subsequent malignancies
    Engels