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U. Veronesi, G. Paganelli, G. Viale, A. Luini, S. Zurrida, V. Galimberti, M. Intra, P. Veronesi, C. Robertson, P. Maisonneuve, G. Renne, C. Cicco, F. Lucia, R. Gennari (2003)
A randomized comparison of sentinel-node biopsy with routine axillary dissection in breast cancer.The New England journal of medicine, 349 6
K. Anan, S. Mitsuyama, K. Tamae, K. Nishihara, Toshimitsu Iwashita, Yuji Abe, T. Ihara, S. Toyoshima (2000)
Axillary lymph node metastases in patients with small carcinomas of the breast: is accurate prediction possible?The European journal of surgery = Acta chirurgica, 166 8
J. Lee, Sung Kim, Y. Suh, B. Shim, Hoon‐Kyo Kim (2010)
Predictors of axillary lymph node metastases (ALNM) in a Korean population with T1-2 breast carcinoma: triple negative breast cancer has a high incidence of ALNM irrespective of the tumor size.Cancer research and treatment : official journal of Korean Cancer Association, 42 1
A. Chagpar, Robert Martin, C. Scoggins, David Carlson, Alison Laidley, S. El-Eid, Terre Mcglothin, R. Noyes, P. Ley, T. Tuttle, K. McMasters (2005)
Factors predicting failure to identify a sentinel lymph node in breast cancer.Surgery, 138 1
G. Santamaría, M. Velasco, X. Farré, J. Vanrell, A. Cardesa, P. Fernandez (2005)
Power Doppler sonography of invasive breast carcinoma: does tumor vascularization contribute to prediction of axillary status?Radiology, 234 2
J. Massengale, R. Brem (2002)
Use of Ultrasound in Breast DiseaseUltrasound Quarterly, 18
Qin Li, Ling Wang, Haojie Wu, Xi-Xiao Wei, Yajie Duan, Lingyao Xu, Zheng Yang, Liu Liu (2015)
Controlled Study of Traditional Ultrasound and Ultrasound Elastography on the Diagnosis of Breast MassesUltrasound Quarterly, 31
J. Youk, E. Son, Jin Chung, Jeong-Ah Kim, Eun-Kyung Kim (2012)
Triple-negative invasive breast cancer on dynamic contrast-enhanced and diffusion-weighted MR imaging: comparison with other breast cancer subtypesEuropean Radiology, 22
J. Cools-Lartigue, S. Meterissian (2011)
Accuracy of Axillary Ultrasound in the Diagnosis of Nodal Metastasis in Invasive Breast Cancer: A ReviewWorld Journal of Surgery, 36
J Clin Oncol, 25
I. Olivotto, Jeremy Jackson, D. Mates, Sandra Andersen, Warren Davidson, C. Bryce, J. Ragaz (1998)
Prediction of axillary lymph node involvement of women with invasive breast carcinomaCancer, 83
Y. Park, J. Youk, E. Son, H. Gweon, Jeong-Ah Kim (2014)
Comparison of hormonal receptor and HER2 status between ultrasound-guided 14-gauge core needle biopsy and surgery in breast cancer patientsUltrasonography, 33
Jia-Long Wu, H. Tseng, Li-Heng Yang, Hwa-Koon Wu, S. Kuo, Shou-Tung Chen, Dar-Ren Chen (2014)
Prediction of axillary lymph node metastases in breast cancer patients based on pathologic information of the primary tumorMedical Science Monitor : International Medical Journal of Experimental and Clinical Research, 20
R. Hooley, Liva Andrejeva, L. Scoutt (2011)
Breast Cancer Screening and Problem Solving Using Mammography, Ultrasound, and Magnetic Resonance ImagingUltrasound Quarterly, 27
Nicholas Howland, T. Driver, Michael Sedrak, Xianfeng Wen, W. Dong, S. Hatch, M. Eltorky, C. Chao (2013)
Lymph node involvement in immunohistochemistry-based molecular classifications of breast cancer.The Journal of surgical research, 185 2
Seho Park, J. Koo, M. Kim, H. Park, Jun Lee, Jong Lee, Seung Kim, Byeong-Woo Park (2012)
Characteristics and outcomes according to molecular subtypes of breast cancer as classified by a panel of four biomarkers using immunohistochemistry.Breast, 21 1
R. Siegel, Jiemin Ma, Zhaohui Zou, A. Jemal (2014)
Cancer statistics, 2014CA: A Cancer Journal for Clinicians, 64
J Med Assoc Thai, 94
S. Crabb, M. Cheang, S. Leung, T. Immonen, T. Nielsen, D. Huntsman, C. Bajdik, S. Chia (2008)
Basal breast cancer molecular subtype predicts for lower incidence of axillary lymph node metastases in primary breast cancer.Clinical breast cancer, 8 3
D. Allred, J. Harvey, M. Berardo, G. Clark (1998)
Prognostic and predictive factors in breast cancer by immunohistochemical analysis.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 11 2
Cancer, 79
L. Tan, Y. Tan, Derrick Heng, M.Y.P. Chan (2005)
Predictors of axillary lymph node metastases in women with early breast cancer in Singapore.Singapore medical journal, 46 12
G. Lyman, A. Giuliano, M. Somerfield, A. Benson, D. Bodurka, H. Burstein, A. Cochran, H. Cody, S. Edge, S. Galper, J. Hayman, Theodore Kim, Cheryl Perkins, D. Podoloff, V. Sivasubramaniam, R. Turner, R. Wahl, D. Weaver, A. Wolff, E. Winer (2005)
American Society of Clinical Oncology guideline recommendations for sentinel lymph node biopsy in early-stage breast cancer.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 23 30
I. Langer, U. Guller, G. Berclaz, O. Koechli, G. Schaer, M. Fehr, T. Hess, D. Oertli, L. Bronz, B. Schnarwyler, E. Wight, U. Uehlinger, E. Infanger, D. Burger, M. Zuber (2007)
Morbidity of Sentinel Lymph Node Biopsy (SLN) Alone Versus SLN and Completion Axillary Lymph Node Dissection After Breast Cancer Surgery: A Prospective Swiss Multicenter Study on 659 PatientsAnnals of Surgery, 245
Gisela Helms, Thorsten Kühn, L. Moser, E. Remmel, Rolf Kreienberg (2009)
Shoulder-arm morbidity in patients with sentinel node biopsy and complete axillary dissection--data from a prospective randomised trial.European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 35 7
B. Weigelt, J. Reis-Filho (2010)
Molecular profiling currently offers no more than tumour morphology and basic immunohistochemistryBreast Cancer Research : BCR, 12
S. Mussurakis, D. Buckley, A. Horsman (1997)
Prediction of axillary lymph node status in invasive breast cancer with dynamic contrast-enhanced MR imaging.Radiology, 203 2
N. Houssami, S. Ciatto, R. Turner, H. Cody, P. Macaskill (2011)
Preoperative Ultrasound-Guided Needle Biopsy of Axillary Nodes in Invasive Breast Cancer: Meta-Analysis of Its Accuracy and Utility in Staging the AxillaAnnals of Surgery, 254
N. Patani, M. Dwek, M. Douek (2007)
Predictors of axillary lymph node metastasis in breast cancer: a systematic review.European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 33 4
A. Spitale, P. Mazzola, D. Soldini, L. Mazzucchelli, A. Bordoni (2009)
Breast cancer classification according to immunohistochemical markers: clinicopathologic features and short-term survival analysis in a population-based study from the South of Switzerland.Annals of oncology : official journal of the European Society for Medical Oncology, 20 4
B. Calster, I. Bempt, M. Drijkoningen, N. Pochet, Jiqiu Cheng, S. Huffel, Wouter Hendrickx, J. Decock, Huei-Jean Huang, K. Leunen, F. Amant, P. Berteloot, R. Paridaens, H. Wildiers, E. Limbergen, C. Weltens, D. Timmerman, T. Gorp, A. Smeets, W. Bogaert, I. Vergote, M. Christiaens, P. Neven (2008)
Axillary lymph node status of operable breast cancers by combined steroid receptor and HER-2 status: triple positive tumours are more likely lymph node positiveBreast Cancer Research and Treatment, 113
Antonio Wolff, M. Hammond, Jared Schwartz, K. Hagerty, D. Allred, Richard Cote, M. Dowsett, P. Fitzgibbons, Wedad Hanna, A. Langer, L. McShane, S. Paik, M. Pegram, Edith Perez, Michael Press, A. Rhodes, C. Sturgeon, S. Taube, R. Tubbs, Gail Vance, Marc Vijver, Thomas Wheeler, Daniel Hayes (2006)
American Society of Clinical Oncology/College of American Pathologists guideline recommendations for human epidermal growth factor receptor 2 testing in breast cancer.Archives of pathology & laboratory medicine, 131 1
G. Viale, S. Zurrida, E. Maiorano, G. Mazzarol, G. Pruneri, G. Paganelli, P. Maisonneuve, U. Veronesi (2005)
Predicting the status of axillary sentinel lymph nodes in 4351 patients with invasive breast carcinoma treated in a single institutionCancer, 103
C. Gajdos, P. Tartter, I. Bleiweiss (1999)
Lymphatic invasion, tumor size, and age are independent predictors of axillary lymph node metastases in women with T1 breast cancers.Annals of surgery, 230 5
Abstract This study was to investigate clinicopathological features including immunohistochemical subtype and radiological factors of primary breast cancer to predict axillary lymph node metastasis (ALNM) and preoperative risk stratification. From June 2004 to May 2014, 369 breast cancer patients (mean age, 54.7 years; range, 29–82 years) who underwent surgical axillary node sampling were included. Two radiologists retrospectively reviewed clinicopathological features, initial mammography, and initial breast ultrasonography (US). Univariate and multivariate logistic regression analyses were used to evaluate associations between ALNM and variables. Odds ratio with 95% confidence interval and risk of ALNM were calculated. Among 369 patients, 117 (31.7%) had ALNM and 252 (68.3%) had no ALNM revealed surgically. On multivariate analysis, four factors showed positive association with ALNM: the presence of symptoms (P < 0.001), triple-negative breast cancer subtype (P = 0.001), mass size on US (>10 mm, P < 0.001), and Breast Imaging Reporting and Data System category on US (≥4c, P < 0.001). The significant risk of ALNM was particularly seen in patients with two or more factors (2, P = 0.013; 3, P < 0.001; 4, P < 0.001).The estimated risks of ALNM increased in patients with two, three, and four factors with odds ratios of 5.5, 14.3, and 60.0, respectively. The presence of symptoms, triple-negative breast cancer subtype, larger size mass on US (>10 mm), and higher Breast Imaging Reporting and Data System category on US (≥4c) were positively associated with ALNM. Radiologically, US findings are significant factors that can affect the decision making process regarding ALNM. Based on risk stratification, the possibility of ALNM can be better predicted if 2 or more associated factors existed preoperatively.
Ultrasound Quarterly – Wolters Kluwer Health
Published: Jul 14, 2016
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