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Review of Terminal Deoxynucleotidyl Transferase Biological Aspects, Methods of Detection, and Selected Diagnostic Applications

Review of Terminal Deoxynucleotidyl Transferase Biological Aspects, Methods of... Terminal deoxynucleotidyl transferase (TdT) is a wellestablished marker of immature hematopoietic cells which is widely used for the diagnosis and characterization of acute leukemias and lymphoid neoplasms. In this review we describe the biology and histopathology of TdT, including a critical discussion of the clinical applications and the various technical approaches for analyzing different pathologic samples. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Applied Immunohistochemistry & Molecular Morphology Wolters Kluwer Health

Review of Terminal Deoxynucleotidyl Transferase Biological Aspects, Methods of Detection, and Selected Diagnostic Applications

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ISSN
1062-3345
eISSN
1533-4058

Abstract

Terminal deoxynucleotidyl transferase (TdT) is a wellestablished marker of immature hematopoietic cells which is widely used for the diagnosis and characterization of acute leukemias and lymphoid neoplasms. In this review we describe the biology and histopathology of TdT, including a critical discussion of the clinical applications and the various technical approaches for analyzing different pathologic samples.

Journal

Applied Immunohistochemistry & Molecular Morphology – Wolters Kluwer Health

Published: Jan 1, 1995

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