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Relationship between Cortisol and Cholesterol in Men with Coronary Artery Disease and Type A Behavior

Relationship between Cortisol and Cholesterol in Men with Coronary Artery Disease and Type A... To further understand the hormonal mechanisms linking behavior pattern and coronary artery disease (CAD), we Investigated the relationship between 0930-hour plasma cortisol and cholesterol In relatively young males who had undergone coronary anglography and In a subgroup of Individuals who had undergone the structured interview for classification of behavior pattern. A statistically significant association (p< 0.05) was found between cortisol and cholesterol for Individuals who had either minimal CAD (20&percnt; to 49&percnt; narrowing) or significant CAD (&ges;50&percnt; narrowing), but not for subjects without CAD. An association between cortisol and cholesterol was also found to be significant for the subgroup of individuals with Type A-1 behavior pattern, but not for those with Type A-2, X, or B behavior patterns. The findings suggest that hormonal mechanisms involving cortisol and cholesterol metabolism may be operative In Individuals with CAD as well as In Individuals with Type A-1 behavior. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Arteriosclerosis Wolters Kluwer Health

Relationship between Cortisol and Cholesterol in Men with Coronary Artery Disease and Type A Behavior

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Copyright
© 1984 by American Heart Association, Inc.
ISSN
0276-5047

Abstract

To further understand the hormonal mechanisms linking behavior pattern and coronary artery disease (CAD), we Investigated the relationship between 0930-hour plasma cortisol and cholesterol In relatively young males who had undergone coronary anglography and In a subgroup of Individuals who had undergone the structured interview for classification of behavior pattern. A statistically significant association (p< 0.05) was found between cortisol and cholesterol for Individuals who had either minimal CAD (20&percnt; to 49&percnt; narrowing) or significant CAD (&ges;50&percnt; narrowing), but not for subjects without CAD. An association between cortisol and cholesterol was also found to be significant for the subgroup of individuals with Type A-1 behavior pattern, but not for those with Type A-2, X, or B behavior patterns. The findings suggest that hormonal mechanisms involving cortisol and cholesterol metabolism may be operative In Individuals with CAD as well as In Individuals with Type A-1 behavior.

Journal

ArteriosclerosisWolters Kluwer Health

Published: Jan 1, 1984

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