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BAC SYMPOSIUM Radiographic Imaging of Bronchioloalveolar Carcinoma: Screening, Patterns of Presentation and Response Assessment David R. Gandara, MD,* Denise Aberle, MD,† Derick Lau, MD, PhD,‡ James Jett, MD,‡ Tim Akhurst, MD, PhD,§ James Mulshine, MD, Christine Berg, MD,¶ and Edward F. Patz, Jr, MD# ronchioloalveolar carcinoma (BAC) is a previously rare Abstract: Bronchioloalveolar carcinoma (BAC) is a previously Bpathologic subtype of adenocarcinoma that seems to be uncommon subset of adenocarcinoma with unique epidemiology, steadily increasing in incidence. In one report, BAC rose pathology, radiographic presentation, clinical features, and natural fourfold during the period of 1955 to 1990. Compared with history compared with other non-small cell lung cancer (NSCLC) other subtypes of non-small cell lung cancer (NSCLC), BAC subtypes. Classically, BAC demonstrates a relatively slow growth is characterized by a distinct clinical presentation, radio- pattern and indolent clinical course. However, in a subset of patients, 2 graphic appearance, and natural history. Further distinguish- rapid growth and death from bilateral diffuse consolidative disease ing BAC from other types of NSCLC is a higher percentage occurs within months of diagnosis or recurrence. Recent data sug- of women, a younger age distribution, and a higher incidence gest that the incidence of BAC is
Journal of Thoracic Oncology – Wolters Kluwer Health
Published: Nov 1, 2006
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