Access the full text.
Sign up today, get DeepDyve free for 14 days.
Gongxiong Wu, Weiguo Hu, A. Shahsafaei, Wenping Song, M. Dobarro, G. Sukhova, R. Bronson, G. Shi, R. Rother, J. Halperin, X. Qin (2009)
Complement Regulator CD59 Protects Against Atherosclerosis by Restricting the Formation of Complement Membrane Attack ComplexCirculation Research, 104
J. Wiśniewski, F. Gaugaz (2015)
Fast and sensitive total protein and Peptide assays for proteomic analysis.Analytical chemistry, 87 8
T. Naruko, M. Ueda, K. Haze, A. Wal, C. Loos, A. Itoh, R. Komatsu, Y. Ikura, M. Ogami, Y. Shimada, S. Ehara, M. Yoshiyama, K. Takeuchi, J. Yoshikawa, A. Becker (2002)
Neutrophil Infiltration of Culprit Lesions in Acute Coronary SyndromesCirculation: Journal of the American Heart Association, 106
S. Pitsilos, J. Hunt, E. Mohler, Anand Prabhakar, M. Poncz, Jennine Dawicki, T. Khalapyan, Megan L.Wolfe, R. Fairman, M. Mitchell, J. Carpenter, M. Golden, D. Cines, B. Sachais (2003)
Platelet factor 4 localization in carotid atherosclerotic plaques: correlation with clinical parametersThrombosis and Haemostasis, 90
Felipe Leprevost, Sarah Haynes, D. Avtonomov, Hui-Yin Chang, A. Shanmugam, Dattatreya Mellacheruvu, Andy Kong, A. Nesvizhskii (2020)
Philosopher: a versatile toolkit for shotgun proteomics data analysisNature Methods, 17
(2017)
MSFragger: ultrafast and comprehensive peptide identification in mass spectrometry-based proteomics
Matthew Chambers, B. MacLean, Robert Burke, Dario Amodei, D. Ruderman, S. Neumann, L. Gatto, Bernd Fischer, Brian Pratt, Jarrett Egertson, Katherine Hoff, Darren Kessner, Natalie Tasman, Nicholas Shulman, Barbara Frewen, Tahmina Baker, M. Brusniak, C. Paulse, D. Creasy, Lisa Flashner, Kian Kani, C. Moulding, S. Seymour, L. Nuwaysir, B. Lefebvre, F. Kuhlmann, J. Roark, Paape Rainer, Suckau Detlev, T. Hemenway, A. Huhmer, J. Langridge, Brian Connolly, Trey Chadick, K. Holly, Josh Eckels, E. Deutsch, R. Moritz, J. Katz, D. Agus, M. MacCoss, D. Tabb, P. Mallick (2012)
A Cross-platform Toolkit for Mass Spectrometry and ProteomicsNature biotechnology, 30
Department of Emergency Medicine, Herlev and Gentofte Hospital
Tianzhi Wu, Erqiang Hu, Shuangbing Xu, Meijun Chen, Pingfan Guo, Zehan Dai, Tingze Feng, Lang Zhou, Wenli Tang, Li Zhan, X. Fu, Shanshan Liu, Xiaochen Bo, Guangchuang Yu (2021)
clusterProfiler 4.0: A universal enrichment tool for interpreting omics dataThe Innovation, 2
P. Ridker (2017)
Mortality Differences Associated With Treatment Responses in CANTOS and FOURIER: Insights and Implications.Circulation, 137 17
B. Heit, Hani Kim, G. Cosío, Diana Castaño, R. Collins, C. Lowell, K. Kain, W. Trimble, S. Grinstein (2013)
Multimolecular signaling complexes enable Syk-mediated signaling of CD36 internalization.Developmental cell, 24 4
M. Ionita, P. Borne, L. Catanzariti, F. Moll, J. Vries, G. Pasterkamp, A. Vink, D. Kleijn (2010)
High Neutrophil Numbers in Human Carotid Atherosclerotic Plaques Are Associated With Characteristics of Rupture-Prone LesionsArteriosclerosis, Thrombosis, and Vascular Biology, 30
M. Furuhashi, M. Ogura, Megumi Matsumoto, Satoshi Yuda, Atsuko Muranaka, Mina Kawamukai, Akina Omori, Marenao Tanaka, Norihito Moniwa, Hirofumi Ohnishi, S. Saitoh, M. Harada‐Shiba, K. Shimamoto, T. Miura (2017)
Serum FABP5 concentration is a potential biomarker for residual risk of atherosclerosis in relation to cholesterol efflux from macrophagesScientific Reports, 7
G. Hommel (1988)
A stagewise rejective multiple test procedure based on a modified Bonferroni testBiometrika, 75
A. Zernecke, I. Bot, Y. Djalali-Talab, E. Shagdarsuren, K. Bidzhekov, Svenja Meiler, Regina Krohn, A. Schober, M. Sperandio, O. Soehnlein, J. Bornemann, F. Tacke, E. Biessen, C. Weber (2008)
Protective Role of CXC Receptor 4/CXC Ligand 12 Unveils the Importance of Neutrophils in AtherosclerosisCirculation Research, 102
J. Tardif, S. Kouz, D. Waters, O. Bertrand, R. Diaz, A. Maggioni, F. Pinto, R. Ibrahim, H. Gamra, G. Kiwan, C. Berry, J. López-Sendón, P. Ostadal, W. Koenig, D. Angoulvant, J. Grégoire, M. Lavoie, M. Dubé, D. Rhainds, Mylène Provencher, L. Blondeau, Andreas Orfanos, P. L'allier, M. Guertin, F. Roubille (2019)
Efficacy and Safety of Low-Dose Colchicine after Myocardial Infarction.The New England journal of medicine
Yasset Pérez-Riverol, A. Csordas, Jingwen Bai, Manuel Llinares, S. Hewapathirana, D. Kundu, Avinash Inuganti, J. Griss, Gerhard Mayer, M. Eisenacher, Enrique Pérez, J. Uszkoreit, J. Pfeuffer, Timo Sachsenberg, Şule Yılmaz, Shivani Tiwary, J. Cox, E. Audain, Mathias Walzer, Andrew Jarnuczak, Tobias Ternent, A. Brazma, J. Vizcaíno (2018)
The PRIDE database and related tools and resources in 2019: improving support for quantification dataNucleic Acids Research, 47
T. Batth, M. Tollenaere, P. Rüther, A. Gonzalez-Franquesa, B. Prabhakar, Simon Bekker-Jensen, A. Deshmukh, J. Olsen (2018)
Protein Aggregation Capture on Microparticles Enables Multipurpose Proteomics Sample Preparation*Molecular & Cellular Proteomics : MCP, 18
Junxiong Qiu, Yuan Fu, Zhiteng Chen, Lisui Zhang, Ling Li, Diefei Liang, Feng Wei, Zhuzhi Wen, Yajing Wang, S. Liang (2021)
BTK Promotes Atherosclerosis by Regulating Oxidative Stress, Mitochondrial Injury, and ER Stress of MacrophagesOxidative Medicine and Cellular Longevity, 2021
A. Sniderman, G. Thanassoulis, Tamara Glavinovic, A. Navar, M. Pencina, A. Catapano, B. Ference (2019)
Apolipoprotein B Particles and Cardiovascular Disease: A Narrative Review.JAMA cardiology
Matthew Ritchie, B. Phipson, Diabetes-Ling Wu, Yifang Hu, C. Law, Wei Shi, G. Smyth (2015)
limma powers differential expression analyses for RNA-sequencing and microarray studiesNucleic Acids Research, 43
Young Park (2014)
CD36, a scavenger receptor implicated in atherosclerosisExperimental & Molecular Medicine, 46
Fengming Liu, Rupam Sahoo, Xiaowen Ge, Lin Wu, Pamela Ghosh, X. Qin, J. Halperin (2017)
Deficiency of the complement regulatory protein CD59 accelerates the development of diabetes-induced atherosclerosis in mice.Journal of diabetes and its complications, 31 2
Mengmeng Guo, Yi-tong Xu, Zhaoqi Dong, Zihao Zhou, Nathan Cong, Mingming Gao, Wei Huang, Yuhui Wang, George Liu, X. Xian (2020)
Inactivation of Apoc3 by CRISPR/Cas9 Protects Against Atherosclerosis in Hamsters.Circulation Research
M. Bäck, Arif Yurdagul, I. Tabas, K. Öörni, P. Kovanen (2019)
Inflammation and its resolution in atherosclerosis: mediators and therapeutic opportunitiesNature Reviews Cardiology, 16
S. Rahaman, D. Lennon, M. Febbraio, E. Podrez, S. Hazen, R. Silverstein (2006)
A CD36‐dependent signaling cascade is necessary for macrophage foam cell formationThe FASEB Journal, 20
Y. Benjamini, Y. Hochberg (1995)
Controlling the false discovery rate: a practical and powerful approach to multiple testingJournal of the royal statistical society series b-methodological, 57
Fengchao Yu, Sarah Haynes, Guo Teo, D. Avtonomov, Daniel Polasky, A. Nesvizhskii (2020)
Fast quantitative analysis of timsTOF PASEF data with MSFragger and IonQuantbioRxiv
C. Gleissner (2011)
Macrophage Phenotype Modulation by CXCL4 in AtherosclerosisFrontiers in Physiology, 3
Background: Materials extracted from atherosclerotic arteries can disclose data about the molecular pathology of cardiovascular disease, but obtaining such samples is complex and requires invasive surgery. To overcome this barrier, this study investigated whether angioplasty balloons inflated during standard percutaneous coronary interventions retain proteins from treated (dilated) atherosclerotic lesions and whether proteomic analysis of this material could provide data on lesion protein profiles and distinguish between patients with stable and unstable coronary artery disease. Methods: Patients with ST-segment–elevation myocardial infarction and stable angina pectoris were subjected to routine percutaneous coronary interventions. All angioplasty balloons inflated in a coronary artery were collected. Proteins retained on the balloons were extracted and analyzed using shotgun proteomic analysis. Results: Proteomics identified and quantified 1365 unique proteins captured on percutaneous coronary intervention balloons. Control balloons inflated in the ascending aorta showed minimal nonspecific protein binding, indicating specificity to the luminal region of atherosclerotic lesions of the diseased artery wall. Clustering and principal component analyses showed that ST-segment–elevation myocardial infarction and stable angina pectoris subjects could be separated by variations in protein content and abundance. We identified 206 proteins as differentially abundant between ST-segment–elevation myocardial infarction and stable angina pectoris subjects. Pathway analysis indicated several enriched processes in the ST-segment–elevation myocardial infarction group involved in neutrophil-mediated immunity and platelet activation. Conclusions: Disease-related proteins from coronary artery lesions adhere to angioplasty balloons and constitute a source of material for proteomic analysis. This approach can identify proteins and processes occurring in unstable coronary atherosclerotic lesions and suggest novel therapeutic approaches.
Arteriosclerosis Thrombosis and Vascular Biology – Wolters Kluwer Health
Published: Jul 21, 2022
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.