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ORIGINAL ARTICLE Primary Tumor Standardized Uptake Value Measured on F18-Fluorodeoxyglucose Positron Emission Tomography Is of Prediction Value for Survival and Local Control in Non–Small-Cell Lung Cancer Receiving Radiotherapy Meta-Analysis Feifei Na, MD,*†‡ Jingwen Wang, MD,*†‡ Cong Li, MD,*‡ Lei Deng, MD,*†‡ Jianxin Xue, MD, PhD,† and You Lu, MD† (95% CI, 1.34–3.60) for pre-SBRT SUV and post-SBRT SUV , max max Introduction: The 2-[18F]-Fluorodeoxyglucose (FDG) positron respectively. emission tomography (PET/CT) has become an imaging tool for Conclusion: Both pre-RT and post-RT primary tumor SUV can max clinical assessment of tumor, node, metastasis in non–small-cell lung predict the outcome of patients with NSCLC treated with radio- cancer (NSCLC). Primary tumor maximum standardized uptake therapy. Patients with high levels of pre-RT SUV seemed to have max value (SUV ) on F-FDG PET/CT before and after radiation ther- max poorer overall survival and LC. XXX apy (RT) has been studied as a potential prognostic factor for NSCLC Key Words: Primary tumor maximum standardized uptake value, patients receiving radiotherapy. However, the sample sizes of most Prognosis, Non–small-cell lung cancer, Meta-analysis, Radiotherapy. studies were small, and the results of the prediction value of SUV max remained undetermined, which lead us to perform a meta-analysis to (J Thorac Oncol. 2014;9: 834–842) improve the precision in estimating its effect. Methods: We performed a meta-analysis of published literature for
Journal of Thoracic Oncology – Wolters Kluwer Health
Published: Jun 1, 2014
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