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ORIGINAL ARTICLE Primary Immunodeficiency Diseases in Oman: Five Years’ Experience at Sultan Qaboos University Hospital 1 1 2 Salem Al-Tamemi, MD, FRCPC, Ibtisam Elnour, MBBS, FRCPCH, and David Dennison, MBBS, MD and advancements in technical abilities in molecular biology, Background: Primary immunodeficiency diseases (PIDs) are con- plus numerous genetics studies over the last 2 decades, many sidered rare but are generally assumed to be more common in Middle underlying causes of these diseases have become known, Eastern countries. The prevalence and characteristics of PIDs are which has helped in firm diagnosis and the creation of certain unknown in Oman. 1 management plans. Because PIDs are rare and phenotypi- Methods: Sultan Qaboos University Hospital is the national referral cally variable, and many primary physicians are not familiar center for PID in Oman during the study period. Patients were with these disorders, many patients arrive at immunology diagnosed and classified according to the clinical and laboratory specialists too late for proper diagnosis and treatment; often criteria of PID reported by the International Union of Immunological there are complications secondary to manifestations of the Societies Primary Immunodeficiency Diseases Classification Com- disease, which are associated with a compromised quality mittee. A registry was
World Allergy Organization Journal – Wolters Kluwer Health
Published: May 1, 2012
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