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Primary Atypical Carcinoid of the Parietal Pleura Expressing KIT

Primary Atypical Carcinoid of the Parietal Pleura Expressing KIT CASE REPORT Primary Atypical Carcinoid of the Parietal Pleura Expressing KIT Tadashi Terada, MD, PhD carcinoma is frequent and large cell neuroendocrine Abstract: The author reports an extremely rare case of atypical carcinoma is relatively frequent, whereas atypical carci- carcinoid of the pleura expressing KIT. An 81-year-old Japanese noid and typical carcinoid are uncommon. All neuroen- man with emphysema was found to have a mass (3  3  2 cm) docrine carcinomas have malignant potential. Small cell in the left parietal pleura by various imaging modalities. Video- lung carcinoma is very aggressive, and large cell assisted tumorectomy was performed, but could not excise it neuroendocrine carcinoma is also relatively aggressive. completely. Histologically, the tumor was composed of atypical Atypical carcinoid usually shows metastasis, and typical cells arranged in trabecular, ribbon-like, and rosette patterns. carcinoid may show malignant behavior. Mitotic figures and necrosis were present. The tumor cells were Two most common neoplasms of the pleura are argyrophil. Immunohistochemically, the tumor cells were mesothelioma and solitary fibrous tumor. Primary positive for pancytokeratins, cytokeratin (CK) 18, chromogra- neuroendocrine tumors of the pleura are extremely rare; nin (focal), p53, KIT, and Ki67 (labeling = 17%). In contrast, only 4 cases of http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Applied Immunohistochemistry & Molecular Morphology Wolters Kluwer Health

Primary Atypical Carcinoid of the Parietal Pleura Expressing KIT

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Copyright
Copyright © 2013 by Lippincott Williams & Wilkins
ISSN
1541-2016
DOI
10.1097/PAI.0b013e3182242023
pmid
21768876
Publisher site
See Article on Publisher Site

Abstract

CASE REPORT Primary Atypical Carcinoid of the Parietal Pleura Expressing KIT Tadashi Terada, MD, PhD carcinoma is frequent and large cell neuroendocrine Abstract: The author reports an extremely rare case of atypical carcinoma is relatively frequent, whereas atypical carci- carcinoid of the pleura expressing KIT. An 81-year-old Japanese noid and typical carcinoid are uncommon. All neuroen- man with emphysema was found to have a mass (3  3  2 cm) docrine carcinomas have malignant potential. Small cell in the left parietal pleura by various imaging modalities. Video- lung carcinoma is very aggressive, and large cell assisted tumorectomy was performed, but could not excise it neuroendocrine carcinoma is also relatively aggressive. completely. Histologically, the tumor was composed of atypical Atypical carcinoid usually shows metastasis, and typical cells arranged in trabecular, ribbon-like, and rosette patterns. carcinoid may show malignant behavior. Mitotic figures and necrosis were present. The tumor cells were Two most common neoplasms of the pleura are argyrophil. Immunohistochemically, the tumor cells were mesothelioma and solitary fibrous tumor. Primary positive for pancytokeratins, cytokeratin (CK) 18, chromogra- neuroendocrine tumors of the pleura are extremely rare; nin (focal), p53, KIT, and Ki67 (labeling = 17%). In contrast, only 4 cases of

Journal

Applied Immunohistochemistry & Molecular MorphologyWolters Kluwer Health

Published: May 1, 2014

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