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Prevalence and Predictors of Carotid Wall Triple Line Pattern in a General Population Sample

Prevalence and Predictors of Carotid Wall Triple Line Pattern in a General Population Sample Prevalence and Predictors of Carotid Wall Triple Line Pattern in a General Population Sample Andrew Ryabikov, Sofia Malyutina, Julian Halcox, Yuri Nikitin, Michael Marmot, Martin Bobak Objective—Carotid intima-media thickness (IMT) and plaques are markers of atherosclerosis and predict cardiovascular events. A specific sonographic triple line pattern (TLP) of the carotid wall has been identified in different conditions, but its origin and clinical significance are unclear. We examined the prevalence and predictors of TLP in a general population. Methods and Results—The study was conducted in random sample of the general population of Novosibirsk, Russia, within the international Health, Alcohol and Psychosocial Factors in Eastern Europe project. In a subsample of 418 men (aged 45 to 69), carotid IMT, the presence of atherosclerotic plaques, and the presence of TLP were assessed by ultrasound. The prevalence of TLP was 21%. It was associated with IMT (odds ratio9.53 per 1 SD, P0.001) and the presence of plaques (odds ratio2.42, P0.002). Other predictors of TLP in multivariate models included age, systolic blood pressure, total cholesterol, and smoking. In addition, infrequent consumption of high amounts of alcohol approximately doubled the risk of triple pattern. Conclusion—Our findings showed high prevalence of TLP of carotid wall in http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Arteriosclerosis, Thrombosis, and Vascular Biology Wolters Kluwer Health

Prevalence and Predictors of Carotid Wall Triple Line Pattern in a General Population Sample

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Copyright
© 2011 American Heart Association, Inc.
ISSN
1079-5642
eISSN
1524-4636
DOI
10.1161/ATVBAHA.110.218057
pmid
21493889
Publisher site
See Article on Publisher Site

Abstract

Prevalence and Predictors of Carotid Wall Triple Line Pattern in a General Population Sample Andrew Ryabikov, Sofia Malyutina, Julian Halcox, Yuri Nikitin, Michael Marmot, Martin Bobak Objective—Carotid intima-media thickness (IMT) and plaques are markers of atherosclerosis and predict cardiovascular events. A specific sonographic triple line pattern (TLP) of the carotid wall has been identified in different conditions, but its origin and clinical significance are unclear. We examined the prevalence and predictors of TLP in a general population. Methods and Results—The study was conducted in random sample of the general population of Novosibirsk, Russia, within the international Health, Alcohol and Psychosocial Factors in Eastern Europe project. In a subsample of 418 men (aged 45 to 69), carotid IMT, the presence of atherosclerotic plaques, and the presence of TLP were assessed by ultrasound. The prevalence of TLP was 21%. It was associated with IMT (odds ratio9.53 per 1 SD, P0.001) and the presence of plaques (odds ratio2.42, P0.002). Other predictors of TLP in multivariate models included age, systolic blood pressure, total cholesterol, and smoking. In addition, infrequent consumption of high amounts of alcohol approximately doubled the risk of triple pattern. Conclusion—Our findings showed high prevalence of TLP of carotid wall in

Journal

Arteriosclerosis, Thrombosis, and Vascular Biology – Wolters Kluwer Health

Published: Jul 1, 2011

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