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ORIGINAL ARTICLE Preoperative Exercise VO Measurement for Lung Resection Candidates: Results of Cancer and Leukemia Group B Protocol 9238 Gregory M. Loewen, DO,* Dorothy Watson, MS,† Leslie Kohman, MD,‡ James E. Herndon II, PhD,† Hani Shennib, MD,§ Kemp Kernstine, MD, PhD, Jemi Olak, MD,¶ M. Jeffery Mador, MD,* David Harpole, MD,# David Sugarbaker, MD,** and Mark Green, MD†† tients (39%) exhibited at least one cardiorespiratory complication Introduction: A stepwise approach to the functional assessment of postoperatively. We found that patients who had a peak exercise lung resection candidates is widely accepted, and this approach VO of 65% of predicted (or a peak VO /kg 16 ml/min/kg) 2 2 incorporates the measurement of exercise peak VO when spirome- were more likely to suffer complications (p 0.0001) and were try and radionuclear studies suggest medical inoperability. A new also more likely to have a poor outcome (respiratory failure or functional operability (FO) algorithm incorporates peak exercise death) if the peak VO was 15 ml/min/kg (p 0.0356). We also VO earlier in the preoperative assessment to determine which found a subset of 58 patients who did not meet FO algorithm patients require preoperative radionuclear studies. This algorithm criteria for operability,
Journal of Thoracic Oncology – Wolters Kluwer Health
Published: Jul 1, 2007
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