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Preliminary Investigation of the Clinical Significance of Detecting Circulating Tumor Cells Enriched from Lung Cancer Patients

Preliminary Investigation of the Clinical Significance of Detecting Circulating Tumor Cells... ORIGINAL ARTICLE Preliminary Investigation of the Clinical Significance of Detecting Circulating Tumor Cells Enriched from Lung Cancer Patients Chi Wu, MD,* Huaijie Hao, MS,†‡ Longyun Li, MD,* Xiaoyun Zhou, MD,* Zijian Guo, MD,* Li Zhang, MD,* Xiaotong Zhang, MD,* Wei Zhong, MD,* Huiqin Guo, MD, PhD,§ Ross Macrae Bremner, MD, PhD, and Ping Lin, MD, PhD‡ Conclusions: Results of the present study suggest potential clinical Background: Enumeration of circulating tumor cells (CTCs) may utilities of CTC enumeration on lung cancer patients in terms of be valuable for lung cancer treatment and monitoring cancer patient rapid evaluation of chemotherapy effect in real time and monitoring relapse. In the present study we report clinical significance of lung lung cancer recurrence. A large scale of study which is necessary for cancer CTC. further validation of the significance of lung cancer CTC is being Methods: CTCs were enriched from peripheral blood of 47 lung performed. cancer patients by means of a modified enrichment strategy, fol- Key Words: Circulating tumor cell (CTC), Lung cancer, Enrich- lowed by identification with immunofluorescence staining using ment, CT, Chemotherapy. anticytokeratins 18 and 19 monoclonal antibodies. Results: A control group consisted of 18 healthy donors and 13 (J Thorac http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Thoracic Oncology Wolters Kluwer Health

Preliminary Investigation of the Clinical Significance of Detecting Circulating Tumor Cells Enriched from Lung Cancer Patients

Lin, Ping
Journal of Thoracic Oncology , Volume 4 (1) – Jan 1, 2009
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References (29)

ISSN
1556-0864
DOI
10.1097/JTO.0b013e3181914125
pmid
19096303
Publisher site
See Article on Publisher Site

Abstract

ORIGINAL ARTICLE Preliminary Investigation of the Clinical Significance of Detecting Circulating Tumor Cells Enriched from Lung Cancer Patients Chi Wu, MD,* Huaijie Hao, MS,†‡ Longyun Li, MD,* Xiaoyun Zhou, MD,* Zijian Guo, MD,* Li Zhang, MD,* Xiaotong Zhang, MD,* Wei Zhong, MD,* Huiqin Guo, MD, PhD,§ Ross Macrae Bremner, MD, PhD, and Ping Lin, MD, PhD‡ Conclusions: Results of the present study suggest potential clinical Background: Enumeration of circulating tumor cells (CTCs) may utilities of CTC enumeration on lung cancer patients in terms of be valuable for lung cancer treatment and monitoring cancer patient rapid evaluation of chemotherapy effect in real time and monitoring relapse. In the present study we report clinical significance of lung lung cancer recurrence. A large scale of study which is necessary for cancer CTC. further validation of the significance of lung cancer CTC is being Methods: CTCs were enriched from peripheral blood of 47 lung performed. cancer patients by means of a modified enrichment strategy, fol- Key Words: Circulating tumor cell (CTC), Lung cancer, Enrich- lowed by identification with immunofluorescence staining using ment, CT, Chemotherapy. anticytokeratins 18 and 19 monoclonal antibodies. Results: A control group consisted of 18 healthy donors and 13 (J Thorac

Journal

Journal of Thoracic Oncology – Wolters Kluwer Health

Published: Jan 1, 2009

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