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Pathological Vascular Invasion and Tumor Differentiation Predict Cancer Recurrence in Stage ia Non–Small-Cell Lung Cancer After Complete Surgical Resection

Pathological Vascular Invasion and Tumor Differentiation Predict Cancer Recurrence in Stage ia... Anjana JTO ORIGINAL ARTICLE Shimada et al. Pathological Vascular Invasion and Tumor Differentiation  Prediction of Cancer Recurrence in Stage IA NSCLC Predict Cancer Recurrence in Stage IA Non–Small-Cell Lung Cancer After Complete Surgical Resection Yoshihisa Shimada, MD, PhD,* Hisashi Saji, MD, PhD,* Koichi Yoshida, MD, PhD,* Masatoshi Kakihana, MD, PhD,* Hidetoshi Honda, MD, PhD,* Masaharu Nomura, MD, PhD,*† Jitsuo Usuda, MD, PhD,* Naohiro Kajiwara, MD, PhD,* Tatsuo Ohira, MD, PhD,* and Norihiko Ikeda, MD, PhD* he tumor, node, metastasis (TNM) staging system for Introduction: The appropriate therapeutic strategy and postop- Tnon–small-cell lung cancer (NSCLC) is currently the erative management for patients with stage IA non–small-cell lung best confirmed predictor of survival and guide for treatment. cancer (NSCLC) still remain a matter of debate because of the prog- NSCLC patients with pathologic stage IA disease have the nostic heterogeneity of this population, including the risk of cancer best chance of survival, and resection is standard in such recurrence. The objective of the current study was to identify the cases. However, even after curative resection, the 5-year sur- clinicopathological factors that affect overall prognosis and cancer vival rate is between 80% and 87% in pathologic stage IA recurrence of stage IA NSCLC. patients as shown in large-scale Japanese lung cancer stud- http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Thoracic Oncology Wolters Kluwer Health

Pathological Vascular Invasion and Tumor Differentiation Predict Cancer Recurrence in Stage ia Non–Small-Cell Lung Cancer After Complete Surgical Resection

Journal of Thoracic Oncology , Volume 7 (8) – Aug 1, 2012

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Copyright
Copyright © 2012 by the International Association for the Study of Lung Cancer
ISSN
1556-0864
DOI
10.1097/JTO.0b013e31825cca6e
pmid
22673056
Publisher site
See Article on Publisher Site

Abstract

Anjana JTO ORIGINAL ARTICLE Shimada et al. Pathological Vascular Invasion and Tumor Differentiation  Prediction of Cancer Recurrence in Stage IA NSCLC Predict Cancer Recurrence in Stage IA Non–Small-Cell Lung Cancer After Complete Surgical Resection Yoshihisa Shimada, MD, PhD,* Hisashi Saji, MD, PhD,* Koichi Yoshida, MD, PhD,* Masatoshi Kakihana, MD, PhD,* Hidetoshi Honda, MD, PhD,* Masaharu Nomura, MD, PhD,*† Jitsuo Usuda, MD, PhD,* Naohiro Kajiwara, MD, PhD,* Tatsuo Ohira, MD, PhD,* and Norihiko Ikeda, MD, PhD* he tumor, node, metastasis (TNM) staging system for Introduction: The appropriate therapeutic strategy and postop- Tnon–small-cell lung cancer (NSCLC) is currently the erative management for patients with stage IA non–small-cell lung best confirmed predictor of survival and guide for treatment. cancer (NSCLC) still remain a matter of debate because of the prog- NSCLC patients with pathologic stage IA disease have the nostic heterogeneity of this population, including the risk of cancer best chance of survival, and resection is standard in such recurrence. The objective of the current study was to identify the cases. However, even after curative resection, the 5-year sur- clinicopathological factors that affect overall prognosis and cancer vival rate is between 80% and 87% in pathologic stage IA recurrence of stage IA NSCLC. patients as shown in large-scale Japanese lung cancer stud-

Journal

Journal of Thoracic OncologyWolters Kluwer Health

Published: Aug 1, 2012

References