Access the full text.
Sign up today, get DeepDyve free for 14 days.
References for this paper are not available at this time. We will be adding them shortly, thank you for your patience.
Downloaded from http://journals.lww.com/appliedimmunohist by BhDMf5ePHKbH4TTImqenVJ2toCr/9wZZjwPUWvYES9lBjFbu9i0DAnSw4JagSjiU on 10/28/2020 RESEARCH ARTICLE Nottingham-defined Mitotic Score: Comparison With Visual and Image Cytometric Phosphohistone H3 Labeling Indices and Correlation With Oncotype DX Recurrence Score Blazej Zbytek, MD, PhD,*w Cynthia Cohen, MD,w Jason Wang, MD,w Andrew Page, MD,z Daron J. Williams, MD,y and Amy L. Adams, MDw methods studied may be useful in assessing tumor grade, pro- Abstract: Prognosis of breast cancer patients has been de- liferation, and prognosis. termined traditionally by lymph node status, tumor size, and Key Words: breast, mitoses, phosphohistone H3, Oncotype DX histologic grade. In recent years the Oncotype DX recurrence RS score (RS) assay has emerged as an expensive adjunct prognostic tool. Markers of proliferation play a large role in determination (Appl Immunohistochem Mol Morphol 2013;21:48–53) of RS, and we have shown previously that immunohisto- chemical expression of proliferation markers Ki-67 and phos- phohistone H3 (PPH3) correlates with RS. Our current goal is n 2010, an estimated 207,090 new cases of invasive comparison of the hematoxylin and eosin (H&E) mitotic score, Ibreast cancer were expected to be diagnosed in women defined by the Nottingham grading system, with anti-PPH3 in the United States, along with 54,010 new cases of mitotic figure
Applied Immunohistochemistry & Molecular Morphology – Wolters Kluwer Health
Published: Jan 1, 2013
Keywords: breast,mitoses,phosphohistone H3,Oncotype DX RS
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.