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New insights into occupational asthma

New insights into occupational asthma a b b b Louis-Philippe Boulet , Catherine Lemie ` re , Denyse Gautrin and Andre ´ Cartier Purpose of review Introduction To examine recent publications on the types of agents About 9 – 15% of adult-onset asthma is considered attribu- involved in occupational asthma, the mechanisms by which table to occupational exposures [1,2]. Although a large they induce asthma, and how best to evaluate and treat number of agents have been identified as potential indu- workers suspected of this respiratory condition. cers of occupational asthma, various working populations Recent findings remain to be tested with regard to the prevalence of such High rates of occupational asthma and inhalation accidents a health hazard. Furthermore, we need to know more were found in workers in crafts and related occupations in about the mechanisms by which these agents induce the manufacturing industries, and in plant and machine asthma, and how best to evaluate and treat workers operatives; cleaners and construction workers may also be suspected of this respiratory condition. at risk. Further data support a role for CD4 T cells in low- molecular-weight agent-induced asthma, such as with Epidemiology isocyanates, and neurogenic mechanisms may also be Despite some limitations, cross-sectional studies http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Current Opinion in Allergy and Clinical Immunology Wolters Kluwer Health

New insights into occupational asthma

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References (65)

ISSN
1528-4050
eISSN
1473-6322
DOI
10.1097/ACI.0b013e328013ccd8
pmid
17218818
Publisher site
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Abstract

a b b b Louis-Philippe Boulet , Catherine Lemie ` re , Denyse Gautrin and Andre ´ Cartier Purpose of review Introduction To examine recent publications on the types of agents About 9 – 15% of adult-onset asthma is considered attribu- involved in occupational asthma, the mechanisms by which table to occupational exposures [1,2]. Although a large they induce asthma, and how best to evaluate and treat number of agents have been identified as potential indu- workers suspected of this respiratory condition. cers of occupational asthma, various working populations Recent findings remain to be tested with regard to the prevalence of such High rates of occupational asthma and inhalation accidents a health hazard. Furthermore, we need to know more were found in workers in crafts and related occupations in about the mechanisms by which these agents induce the manufacturing industries, and in plant and machine asthma, and how best to evaluate and treat workers operatives; cleaners and construction workers may also be suspected of this respiratory condition. at risk. Further data support a role for CD4 T cells in low- molecular-weight agent-induced asthma, such as with Epidemiology isocyanates, and neurogenic mechanisms may also be Despite some limitations, cross-sectional studies

Journal

Current Opinion in Allergy and Clinical Immunology – Wolters Kluwer Health

Published: Feb 1, 2007

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