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Amalia Enrı ´quez-de-Salamanca and Margarita Calonge Purpose of review Introduction A wide distribution of the eye’s muscarinic receptor system The presence of muscarinic receptors has been described has been found and several roles for the muscarinic system in many ocular tissues and several roles for the muscarinic in the eye proposed, although functional consequences of system in the eye have been proposed [1,2]. Some studies muscarinic receptor activation are not always fully have shown that the expression and/or functioning of characterized. The present paper reviews current muscarinic receptors are involved in some ocular surface knowledge about the presence of muscarinic receptors in diseases, and they are being targeted for the treatment of the ocular surface and the implication of alterations on their several pathologies. The aim of this study is to review expression and/or functioning in eye diseases. recent data about the role for the muscarinic system in the Recent findings ocular surface. Several authors have described alterations in muscarinic receptor subtype expression in the eye under pathological Muscarinic receptors conditions. In conjunctiva of vernal keratoconjunctivitis Muscarinic acetylcholine receptors belong to a family of patients, the expression of muscarinic receptor subtypes is receptors that mediate signal transduction by coupling
Current Opinion in Allergy and Clinical Immunology – Wolters Kluwer Health
Published: Oct 1, 2006
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