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More Evidence for the Survival Benefit of Coronary Revascularization Versus Medical Therapy in Patients With Ischemic Cardiomyopathy and Hibernating Myocardium

More Evidence for the Survival Benefit of Coronary Revascularization Versus Medical Therapy in... Editorial More Evidence for the Survival Benefit of Coronary Revascularization Versus Medical Therapy in Patients With Ischemic Cardiomyopathy and Hibernating Myocardium George A. Beller, MD or many years, it has been recognized that patients Article see p 363 Fwith coronary artery disease (CAD) and left ventricu- All the noninvasive viability imaging techniques in clinical lar (LV) dysfunction who manifest substantial myocardial use can adequately identify hibernating myocardium in patients viability in asynergic myocardial regions have improved LV with ischemic cardiomyopathy. When the relative sensitivities regional and global function, exhibit reverse LV remodel- and specificities of these modalities are compared, PET-FDG ing, and exhibit a reduction in ischemic mitral regurgitation had the highest sensitivity and dobutamine echocardiography and a reduction in heart failure symptoms after revascular- had the highest specificity for detection of viability. A meta- ization. Observational studies using a variety of noninvasive analysis was conducted to determine the optimal cutoff values methodologies for assessment of myocardial viability have for the assessment of viability using these various imaging also shown enhanced survival with revascularization versus techniques for which revascularization would offer a survival medical therapy in such patients. A much quoted meta-anal- benefit in patients with ischemic cardiomyopathy. The http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Circulation: Cardiovascular Imaging Wolters Kluwer Health

More Evidence for the Survival Benefit of Coronary Revascularization Versus Medical Therapy in Patients With Ischemic Cardiomyopathy and Hibernating Myocardium

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References (16)

Copyright
© 2013 American Heart Association, Inc.
ISSN
1941-9651
eISSN
1942-0080
DOI
10.1161/CIRCIMAGING.113.000466
pmid
23696583
Publisher site
See Article on Publisher Site

Abstract

Editorial More Evidence for the Survival Benefit of Coronary Revascularization Versus Medical Therapy in Patients With Ischemic Cardiomyopathy and Hibernating Myocardium George A. Beller, MD or many years, it has been recognized that patients Article see p 363 Fwith coronary artery disease (CAD) and left ventricu- All the noninvasive viability imaging techniques in clinical lar (LV) dysfunction who manifest substantial myocardial use can adequately identify hibernating myocardium in patients viability in asynergic myocardial regions have improved LV with ischemic cardiomyopathy. When the relative sensitivities regional and global function, exhibit reverse LV remodel- and specificities of these modalities are compared, PET-FDG ing, and exhibit a reduction in ischemic mitral regurgitation had the highest sensitivity and dobutamine echocardiography and a reduction in heart failure symptoms after revascular- had the highest specificity for detection of viability. A meta- ization. Observational studies using a variety of noninvasive analysis was conducted to determine the optimal cutoff values methodologies for assessment of myocardial viability have for the assessment of viability using these various imaging also shown enhanced survival with revascularization versus techniques for which revascularization would offer a survival medical therapy in such patients. A much quoted meta-anal- benefit in patients with ischemic cardiomyopathy. The

Journal

Circulation: Cardiovascular ImagingWolters Kluwer Health

Published: May 1, 2013

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