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Mechanisms of allergy and adult asthma

Mechanisms of allergy and adult asthma EDITORIAL COMMENT Stephen Holgate Respiratory Cell and Molecular Biology Research Division, Southampton General combination of these with as yet unidenti®ed factors, Hospital, Southampton, UK coupled with the high allergen exposure that is Correspondence to Professor Stephen Holgate, Respiratory Cell and Molecular encountered in the western lifestyle that will eventually Biology Research Division, Southampton General Hospital, Southampton, UK turn out to be behind the change in demography of Tel: +44 023 80 796 960; fax: +44 023 80 701 771; e-mail: s.holgate@soton.ac.uk allergy; if any of these factors are important, they will Current Opinion in Allergy and Clinical Immunology 2001, 1:47±50 undoubtedly provide the basis for novel preventive measures and treatments. As we enter the post-human 2001 Lippincott Williams & Wilkins genome era, a key target for future research must be for 1528-4050 identi®cation of how these environmental factors interact with speci®c susceptibility genes to tilt the phenotype towards allergy. As the new millennium starts, we are faced with a worldwide epidemic of allergic disease. This appears to A major breakthrough in our understanding of the cut across the full spectrum of allergy to include rhinitis, cellular and mediator mechanisms of allergy has come conjunctivitis, atopic eczema, contact dermatitis, asthma, http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Current Opinion in Allergy and Clinical Immunology Wolters Kluwer Health

Mechanisms of allergy and adult asthma

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Copyright
Copyright © 2001 by Lippincott Williams & Wilkins. All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical, photocopying, recording or otherwise without either the prior written permission of the Publisher or a licence permitting restricted copying issued in the UK by the Copyright Licensing Authority and in the USA by the Copyright Clearance Center. Applications for permission should be addressed to the International Rights Department, Lippincott Williams & Wilkins, 227 East Washington Square, Philadelphia, PA 19106-380, USA, or faxed to (+1) 215 238 4419. 1528-4050/01.
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1528-4050
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1473-6322

Abstract

EDITORIAL COMMENT Stephen Holgate Respiratory Cell and Molecular Biology Research Division, Southampton General combination of these with as yet unidenti®ed factors, Hospital, Southampton, UK coupled with the high allergen exposure that is Correspondence to Professor Stephen Holgate, Respiratory Cell and Molecular encountered in the western lifestyle that will eventually Biology Research Division, Southampton General Hospital, Southampton, UK turn out to be behind the change in demography of Tel: +44 023 80 796 960; fax: +44 023 80 701 771; e-mail: s.holgate@soton.ac.uk allergy; if any of these factors are important, they will Current Opinion in Allergy and Clinical Immunology 2001, 1:47±50 undoubtedly provide the basis for novel preventive measures and treatments. As we enter the post-human 2001 Lippincott Williams & Wilkins genome era, a key target for future research must be for 1528-4050 identi®cation of how these environmental factors interact with speci®c susceptibility genes to tilt the phenotype towards allergy. As the new millennium starts, we are faced with a worldwide epidemic of allergic disease. This appears to A major breakthrough in our understanding of the cut across the full spectrum of allergy to include rhinitis, cellular and mediator mechanisms of allergy has come conjunctivitis, atopic eczema, contact dermatitis, asthma,

Journal

Current Opinion in Allergy and Clinical Immunology – Wolters Kluwer Health

Published: Feb 1, 2001

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