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Material Density Hepatic Steatosis Quantification on Intravenous Contrast-Enhanced Rapid Kilovolt (Peak)–Switching Single-Source Dual-Energy Computed Tomography

Material Density Hepatic Steatosis Quantification on Intravenous Contrast-Enhanced Rapid Kilovolt... ORIGINAL ARTICLE Material Density Hepatic Steatosis Quantification on Intravenous Contrast-Enhanced Rapid Kilovolt (Peak)–Switching Single-Source Dual-Energy Computed Tomography Bhavik N. Patel, MD,* Rekha Anjali Kumbla, MD,† Lincoln L. Berland, MD,‡ Naomi S. Fineberg, PhD,§ and Desiree E. Morgan, MD‡ children in the United States with prevalence of 25% and Purpose: The purpose of this study was to evaluate intravenous (IV) 1–3 10%, respectively. The severity of hepatic steatosis and the contrast-enhanced single-source rapid kilovolt (peak)–switching dual- quantification of fat within the liver are important in assessing energy (RSDE) multidetector computed tomography (CT) material density hepatomegaly and the risk for developing cirrhosis as well as assessment of hepatic steatosis compared to conventional unenhanced determining liver transplantation and hepatic resection out- (CU) Multidetector computed tomography (MDCT). 4,5 comes. In most cases, a steatotic liver remains free of inflam- Materials and Methods: This is an institutional review board– mation; however, in 10% to 20% of cases, inflammation will approved intrapatient study of 363 consecutive adults (189 men, 174 women; develop, leading to nonalcoholic steatohepatitis (NASH), a mean age, 59 years) evaluated with multiphasic IV abdominal RSDE. term initially coined by Ludwig et al. Nonalcoholic steato- Material density virtual unenhanced water and fat hepatic http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Computer Assisted Tomography Wolters Kluwer Health

Material Density Hepatic Steatosis Quantification on Intravenous Contrast-Enhanced Rapid Kilovolt (Peak)–Switching Single-Source Dual-Energy Computed Tomography

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References (38)

Copyright
Copyright © 2013 by Lippincott Williams & Wilkins
ISSN
0363-8715
eISSN
1532-3145
DOI
10.1097/RCT.0000000000000027
pmid
24270112
Publisher site
See Article on Publisher Site

Abstract

ORIGINAL ARTICLE Material Density Hepatic Steatosis Quantification on Intravenous Contrast-Enhanced Rapid Kilovolt (Peak)–Switching Single-Source Dual-Energy Computed Tomography Bhavik N. Patel, MD,* Rekha Anjali Kumbla, MD,† Lincoln L. Berland, MD,‡ Naomi S. Fineberg, PhD,§ and Desiree E. Morgan, MD‡ children in the United States with prevalence of 25% and Purpose: The purpose of this study was to evaluate intravenous (IV) 1–3 10%, respectively. The severity of hepatic steatosis and the contrast-enhanced single-source rapid kilovolt (peak)–switching dual- quantification of fat within the liver are important in assessing energy (RSDE) multidetector computed tomography (CT) material density hepatomegaly and the risk for developing cirrhosis as well as assessment of hepatic steatosis compared to conventional unenhanced determining liver transplantation and hepatic resection out- (CU) Multidetector computed tomography (MDCT). 4,5 comes. In most cases, a steatotic liver remains free of inflam- Materials and Methods: This is an institutional review board– mation; however, in 10% to 20% of cases, inflammation will approved intrapatient study of 363 consecutive adults (189 men, 174 women; develop, leading to nonalcoholic steatohepatitis (NASH), a mean age, 59 years) evaluated with multiphasic IV abdominal RSDE. term initially coined by Ludwig et al. Nonalcoholic steato- Material density virtual unenhanced water and fat hepatic

Journal

Journal of Computer Assisted Tomography – Wolters Kluwer Health

Published: Nov 1, 2013

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