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- Publisher
- Wolters Kluwer Health
- Copyright
- Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.
- ISSN
- 1087-2418
- eISSN
- 1531-7013
- DOI
- 10.1097/mot.0000000000000950
- Publisher site
- See Article on Publisher Site
Abstract
Purpose of reviewCardiovascular disease is one of the leading causes of death in solid organ transplant (SOT) recipients. Early identification of cardiovascular risk factors and their adequate management in this population is key for prevention and improved outcomes.Recent findingsApproximately 80% of SOT present one or more cardiovascular risk factors, with increasing prevalence with time posttransplantation. They are due to the interplay of pretransplant conditions and metabolic consequences of immunosuppressive agents, mainly corticosteroids and calcineurin inhibitors. Among the pharmacological management strategies, statins have shown an important protective effect in SOT.SummaryStrict surveillance of cardiovascular risk factors is recommended in SOT due to their high prevalence and prognostic implications. Further studies on the best managements strategies in this population are needed.
Journal
Current Opinion in Organ Transplantation – Wolters Kluwer Health
Published: Feb 15, 2022