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Downloaded from http://journals.lww.com/topicsinmri by BhDMf5ePHKbH4TTImqenVJ2toCr/9wZZjwPUWvYES9lBjFbu9i0DAnSw4JagSjiU on 10/30/2020 ORIGINAL ARTICLE Magnetic Resonance Imaging for Hypertrophic Cardiomyopathy Update Andy Kar Wai Chan, MD, Bhanusupriya Somarouthu, MD, and Brian Ghoshhajra, MD, MBA Histologically, HCM manifests as myocyte disarray, abnor- Objectives: Hypertrophic cardiomyopathy (HCM) is a genetic disease mal intracellular calcium reuptake, and microvascular ischemia of the myocardium. Although many patients remain asymptomatic, 2 resulting in cell death and progressive fibrosis. Both the myo- sudden cardiac death could be the first manifestation of HCM. Magnetic cyte disarray and myocardial fibrosis act as foci for ventricular resonance imaging (MRI) plays an important role in the diagnosis and 2 arrhythmia, which is the primary mechanism for SCD. Macro- management of this disease. scopically, ventricular hypertrophy is evident, resulting in alter- Methods: The epidemiology, pathophysiology, and diagnosis of HCM ations of load and contractility of the LV. This ultimately leads to will be briefly reviewed. This is followed by a discussion on the role of multiple interrelated abnormalities, including LVOT obstruction cardiac MRI, recommended protocol, typical imaging findings of HCM, with or without systolic anterior motion (SAM) of the anterior and advanced MRI techniques. leaflet of the mitral valve, mitral regurgitation, diastolic dysfunc- Conclusions: Although MRI
Topics in Magnetic Resonance Imaging – Wolters Kluwer Health
Published: Feb 1, 2014
Keywords: cardiac MRI,cardiac MR,cardiac magnetic resonance imaging,cardiac magnetic resonance,cardiac magnetic resonance,hypertrophic cardiomyopathy,HCM
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