Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Loss of Annexin A1 Expression in Breast Cancer Progression

Loss of Annexin A1 Expression in Breast Cancer Progression RESEARCH ARTICLE Loss of Annexin A1 Expression in Breast Cancer Progression Ying Cao, MD, PhD, Yong Li, PhD, Marcia Edelweiss, MD, Banu Arun, MD, Daniel Rosen, MD, Erika Resetkova, MD, Yun Wu, MD, PhD, Jinsong Liu, MD, PhD, Aysegul Sahin, MD, and Constance T. Albarracin, MD, PhD reast cancer is the most common cancer among Background: Annexin A1 (ANXA1) is a potential marker of BAmerican women, with 178,480 new cases and 40,460 development of breast cancer. However, previous studies of deaths from breast cancer estimated to occur in the ANXA1 expression in primary breast carcinoma and lymph United States in the year 2007. It is widely accepted that node metastasis have yielded conflicting results. Therefore, to breast cancer is a multistep process with invasive breast accurately characterize the ANXA1 expression pattern, we used carcinoma being frequently preceded by or associated 2,3 microarray analysis and matched patient samples to evaluate with in situ lesions and atypical hyperplasias. Malig- progressive alterations in ANXA1 protein expression during nant transformation in breast cancer involves altered malignant transformation and metastasis. expression of proteins, which could play an important role in the cancer progression. Design: We constructed a tissue microarray using 82 pairs of One http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Applied Immunohistochemistry & Molecular Morphology Wolters Kluwer Health

Loss of Annexin A1 Expression in Breast Cancer Progression

Loading next page...
 
/lp/wolters-kluwer-health/loss-of-annexin-a1-expression-in-breast-cancer-progression-RddCMz93y3
ISSN
1541-2016
DOI
10.1097/PAI.0b013e31817432c3
pmid
18776816
Publisher site
See Article on Publisher Site

Abstract

RESEARCH ARTICLE Loss of Annexin A1 Expression in Breast Cancer Progression Ying Cao, MD, PhD, Yong Li, PhD, Marcia Edelweiss, MD, Banu Arun, MD, Daniel Rosen, MD, Erika Resetkova, MD, Yun Wu, MD, PhD, Jinsong Liu, MD, PhD, Aysegul Sahin, MD, and Constance T. Albarracin, MD, PhD reast cancer is the most common cancer among Background: Annexin A1 (ANXA1) is a potential marker of BAmerican women, with 178,480 new cases and 40,460 development of breast cancer. However, previous studies of deaths from breast cancer estimated to occur in the ANXA1 expression in primary breast carcinoma and lymph United States in the year 2007. It is widely accepted that node metastasis have yielded conflicting results. Therefore, to breast cancer is a multistep process with invasive breast accurately characterize the ANXA1 expression pattern, we used carcinoma being frequently preceded by or associated 2,3 microarray analysis and matched patient samples to evaluate with in situ lesions and atypical hyperplasias. Malig- progressive alterations in ANXA1 protein expression during nant transformation in breast cancer involves altered malignant transformation and metastasis. expression of proteins, which could play an important role in the cancer progression. Design: We constructed a tissue microarray using 82 pairs of One

Journal

Applied Immunohistochemistry & Molecular MorphologyWolters Kluwer Health

Published: Dec 1, 2008

There are no references for this article.