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Liver Steatosis Quantification Using Magnetic Resonance Imaging A Prospective Comparative Study With Liver Biopsy

Liver Steatosis Quantification Using Magnetic Resonance Imaging A Prospective Comparative Study... ORIGINAL ARTICLE Liver Steatosis Quantification Using Magnetic Resonance Imaging: A Prospective Comparative Study With Liver Biopsy Nicolas Mennesson, MD,* Je´roˆme Dumortier, MD, PhD,Þ§ Vale´rie Hervieu, MD,þ§ Laurent Milot, MD,* Olivier Guillaud, MD,Þ Jean-Yves Scoazec, MD, PhD,þ§ and Frank Pilleul, PhD, MD*§ quired when an assessment of activity and severity of NAFLD Background and Aims: To prospectively determine the accuracy is considered necessary. of liver fat quantification with magnetic resonance imaging (MRI). In the United States, approximately 47 million individuals Patients and Methods: The population consisted of 40 patients 3 are estimated to have a metabolic syndrome : fatty infiltration (mean age, 52.5 years; range, 23Y78 years). The same day, all patients of the liver can be detected in up to 12% to 15% in this popula- underwent MRI and ultrasonography-guided liver biopsy. The histolog- 4 tion, and 3% to 4% of patients with NAFLD have steatohep- ical evaluation of steatosis was performed by an experienced liver atitis. Nonalcoholic steatohepatitis was originally believed to pathologist blinded to the MRI results. On T1-weighted in- and opposed- be a benign disease. However, it has been recently shown that phase images, one radiologist, experienced in abdominal imaging, 5 NASH could lead to irreversible http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Computer Assisted Tomography Wolters Kluwer Health

Liver Steatosis Quantification Using Magnetic Resonance Imaging A Prospective Comparative Study With Liver Biopsy

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ISSN
0363-8715
eISSN
1532-3145
DOI
10.1097/RCT.0b013e318199d883
pmid
19820490
Publisher site
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Abstract

ORIGINAL ARTICLE Liver Steatosis Quantification Using Magnetic Resonance Imaging: A Prospective Comparative Study With Liver Biopsy Nicolas Mennesson, MD,* Je´roˆme Dumortier, MD, PhD,Þ§ Vale´rie Hervieu, MD,þ§ Laurent Milot, MD,* Olivier Guillaud, MD,Þ Jean-Yves Scoazec, MD, PhD,þ§ and Frank Pilleul, PhD, MD*§ quired when an assessment of activity and severity of NAFLD Background and Aims: To prospectively determine the accuracy is considered necessary. of liver fat quantification with magnetic resonance imaging (MRI). In the United States, approximately 47 million individuals Patients and Methods: The population consisted of 40 patients 3 are estimated to have a metabolic syndrome : fatty infiltration (mean age, 52.5 years; range, 23Y78 years). The same day, all patients of the liver can be detected in up to 12% to 15% in this popula- underwent MRI and ultrasonography-guided liver biopsy. The histolog- 4 tion, and 3% to 4% of patients with NAFLD have steatohep- ical evaluation of steatosis was performed by an experienced liver atitis. Nonalcoholic steatohepatitis was originally believed to pathologist blinded to the MRI results. On T1-weighted in- and opposed- be a benign disease. However, it has been recently shown that phase images, one radiologist, experienced in abdominal imaging, 5 NASH could lead to irreversible

Journal

Journal of Computer Assisted Tomography – Wolters Kluwer Health

Published: Sep 1, 2009

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