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Letter by Mehmood Regarding Article, “Validation of the Tricuspid Annular Plane Systolic Excursion/Systolic Pulmonary Artery Pressure Ratio for the Assessment of Right Ventricular-Arterial Coupling in Severe Pulmonary Hypertension”

Letter by Mehmood Regarding Article, “Validation of the Tricuspid Annular Plane Systolic... Circulation: Cardiovascular Imaging LETTER TO THE EDITOR Letter by Mehmood Regarding Article, “Validation of the Tricuspid Annular Plane Systolic Excursion/Systolic Pulmonary Artery Pressure Ratio for the Assessment of Right Ventricular-Arterial Coupling in Severe Pulmonary Hypertension” To the Editor: Muddassir Mehmood, In a recent issue of Circulation: Cardiovascular Imaging Tello et al delineated the MD, FACC relationship of pressure-volume loop-derived end-systolic/arterial elastance (Ees/ Ea) with its noninvasive surrogates in severe pulmonary hypertension. The ratio of tricuspid annular plane systolic excursion and systolic pulmonary artery pressure was an independent predictor of Ees/Ea. The authors should be congratulated for putting tricuspid annular plane systolic excursion/systolic pulmonary artery pressure through the rigors of validation and for recognizing the limitations of noninvasive surrogates of right ventricular (RV)-pulmonary artery (PA) coupling. None of the surrogate markers corrected with Ees and the correlation of tricuspid annular plane systolic excursion/systolic pulmonary artery pressure with Ea and Ees/Ea was only moderate. While the prognostic significance of a simple noninvasive metric that gives any insight into RV-PA coupling in pulmonary hypertension is not to be belittled, a biomarker has to be fairly robust and capable of timely serial measurements to help assess and guide management of RV dysfunction in http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Circulation: Cardiovascular Imaging Wolters Kluwer Health

Letter by Mehmood Regarding Article, “Validation of the Tricuspid Annular Plane Systolic Excursion/Systolic Pulmonary Artery Pressure Ratio for the Assessment of Right Ventricular-Arterial Coupling in Severe Pulmonary Hypertension”

Mehmood, Muddassir
Circulation: Cardiovascular Imaging , Volume 12 (11) – Nov 1, 2019
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Publisher
Wolters Kluwer Health
Copyright
© 2019 American Heart Association, Inc.
ISSN
1941-9651
eISSN
1942-0080
DOI
10.1161/CIRCIMAGING.119.010002
Publisher site
See Article on Publisher Site

Abstract

Circulation: Cardiovascular Imaging LETTER TO THE EDITOR Letter by Mehmood Regarding Article, “Validation of the Tricuspid Annular Plane Systolic Excursion/Systolic Pulmonary Artery Pressure Ratio for the Assessment of Right Ventricular-Arterial Coupling in Severe Pulmonary Hypertension” To the Editor: Muddassir Mehmood, In a recent issue of Circulation: Cardiovascular Imaging Tello et al delineated the MD, FACC relationship of pressure-volume loop-derived end-systolic/arterial elastance (Ees/ Ea) with its noninvasive surrogates in severe pulmonary hypertension. The ratio of tricuspid annular plane systolic excursion and systolic pulmonary artery pressure was an independent predictor of Ees/Ea. The authors should be congratulated for putting tricuspid annular plane systolic excursion/systolic pulmonary artery pressure through the rigors of validation and for recognizing the limitations of noninvasive surrogates of right ventricular (RV)-pulmonary artery (PA) coupling. None of the surrogate markers corrected with Ees and the correlation of tricuspid annular plane systolic excursion/systolic pulmonary artery pressure with Ea and Ees/Ea was only moderate. While the prognostic significance of a simple noninvasive metric that gives any insight into RV-PA coupling in pulmonary hypertension is not to be belittled, a biomarker has to be fairly robust and capable of timely serial measurements to help assess and guide management of RV dysfunction in

Journal

Circulation: Cardiovascular Imaging – Wolters Kluwer Health

Published: Nov 1, 2019

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