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Intraocular Metastases—A Review

Intraocular Metastases—A Review Downloaded from http://journals.lww.com/apjoo by BhDMf5ePHKbH4TTImqenVA5KvPVPZ0P5BEgU+IUTEfzO/GUWifn2IfwcEVVH9SSn on 06/02/2020 REVIEW ARTICLE Lazaros Konstantinidis, MD,* and Bertil Damato, MD, PhD, FRCOphth† 1,4 blurred vision or visual loss due to macular or peripapillary Abstract: Intraocular metastases almost invariably arise in the uveal 10 retina involvement or due to exudative retinal detachment. In- tract, mostly in the posterior choroid. They are the most common type of frequently, anteriorly located tumors may tilt the lens, causing intraocular malignancy and often the first sign of tumor dissemination. visual loss. Rarely, they cause painful neovascular glaucoma or Choroidal metastases generally appear as a creamy white or pale yellow 11 metastatic iritis. Interestingly, about 12% of patients with me- mass associated with subretinal fluid and may be multifocal and bilateral. tastasis from lung experience pain in the absence of glaucoma or The most common primary sites are the breast and lung. Diagnosis is aided uveitis, as compared with less than 5% of patients with metastasis by a variety of tests, particularly ultrasonography and optical coherence to- 12,13 from breast. mography. Intraocular biopsy is useful in patients with clinical suspicion of Other symptoms include photopsia, metamorphopsia, and uveal metastasis but no evidence of primary malignancy despite systemic floaters. Diplopia http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png The Asia-Pacific Journal of Ophthalmology Wolters Kluwer Health

Intraocular Metastases—A Review

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References (75)

Publisher
Wolters Kluwer Health
ISSN
2162-0989
eISSN
2475-5028
DOI
10.22608/APO.201712
Publisher site
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Abstract

Downloaded from http://journals.lww.com/apjoo by BhDMf5ePHKbH4TTImqenVA5KvPVPZ0P5BEgU+IUTEfzO/GUWifn2IfwcEVVH9SSn on 06/02/2020 REVIEW ARTICLE Lazaros Konstantinidis, MD,* and Bertil Damato, MD, PhD, FRCOphth† 1,4 blurred vision or visual loss due to macular or peripapillary Abstract: Intraocular metastases almost invariably arise in the uveal 10 retina involvement or due to exudative retinal detachment. In- tract, mostly in the posterior choroid. They are the most common type of frequently, anteriorly located tumors may tilt the lens, causing intraocular malignancy and often the first sign of tumor dissemination. visual loss. Rarely, they cause painful neovascular glaucoma or Choroidal metastases generally appear as a creamy white or pale yellow 11 metastatic iritis. Interestingly, about 12% of patients with me- mass associated with subretinal fluid and may be multifocal and bilateral. tastasis from lung experience pain in the absence of glaucoma or The most common primary sites are the breast and lung. Diagnosis is aided uveitis, as compared with less than 5% of patients with metastasis by a variety of tests, particularly ultrasonography and optical coherence to- 12,13 from breast. mography. Intraocular biopsy is useful in patients with clinical suspicion of Other symptoms include photopsia, metamorphopsia, and uveal metastasis but no evidence of primary malignancy despite systemic floaters. Diplopia

Journal

The Asia-Pacific Journal of Ophthalmology – Wolters Kluwer Health

Published: Mar 1, 2017

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