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a,b,c Philip J. Cooper Centre for Infection, St George’s University of London, Purpose of review London, UK, Instituto de Microbiologia, Universidad To review the findings of recent human studies of the association between helminth San Francisco de Quito, Quito and Centro de Investigaciones FEPIS, Hospital ‘Padre Alberto parasite infections and allergy and discuss their potential relevance to public health. Buffoni’, Quininde´, Esmeraldas Province, Ecuador Recent findings Correspondence to Philip J. Cooper, Casilla 17-14-39, Different helminth parasites may have different effects on allergy that may depend on the Carcelen, Quito, Ecuador timing or intensity of the exposure or host genetic factors. Infections with Trichuris Tel/fax: +593 2 62737158; e-mail: pcooper@sgul.ac.uk trichiura in early life are associated with a reduced prevalence of allergen skin test reactivity later in life and infants of helminth-infected mothers have been reported to Current Opinion in Allergy and Clinical Immunology 2009, 9:29–37 have a reduced prevalence of eczema. Hookworm infection has been associated with a reduced prevalence of asthma in Ethiopia. Several studies have reported that anti-Ascaris IgE is an important risk factor for asthma, but this could be explained by an enhanced ability of atopics to produce IgE. Toxocara infections may be associated with an
Current Opinion in Allergy and Clinical Immunology – Wolters Kluwer Health
Published: Feb 1, 2009
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