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Initial Results of the Use of a Standardized Diagnostic Criteria for Chest Computed Tomography Findings in Coronavirus Disease 2019

Initial Results of the Use of a Standardized Diagnostic Criteria for Chest Computed Tomography... Objective The objective of this study was to assess the initial results of chest computed tomography (CT) standardized diagnostic criteria proposed by the Radiological Society of North America in coronavirus disease 2019 (COVID-19) compared with reverse transcription–polymerase chain reaction (RT-PCR). Methods Seventy-one patients who underwent RT-PCR test for COVID-19 and chest CT within an interval of 4 days or less were included. Seventy-five CTs were reviewed and classified as typical, indeterminate, or atypical appearance or negative for pneumonia by 2 radiologists. With RT-PCR as reference standard, the performance of the CT diagnostic criteria in diagnosing COVID-19 was assessed. Results The prevalence of positive RT-PCR was 45.1%. It was obtained a sensitivity of 83% (95% confidence interval [CI], 78%–89%), a specificity of 97% (95% CI, 92%–99%), an accuracy of 91% (95% CI, 85%–96%), a positive predictive value of 97% (95% CI, 91%–99%), and a negative predictive value of 86% (95% CI, 80%–92%). The diagnostic performance was excellent, considering the area under the curve of 0.92 (95% CI, 0.84–0.99). Conclusions Chest CT standardized diagnostic criteria had high specificity and positive predictive value for the diagnosis of COVID-19 when presenting a typical appearance. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Computer Assisted Tomography Wolters Kluwer Health

Initial Results of the Use of a Standardized Diagnostic Criteria for Chest Computed Tomography Findings in Coronavirus Disease 2019

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References (23)

Publisher
Wolters Kluwer Health
Copyright
Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.
ISSN
0363-8715
eISSN
1532-3145
DOI
10.1097/RCT.0000000000001054
Publisher site
See Article on Publisher Site

Abstract

Objective The objective of this study was to assess the initial results of chest computed tomography (CT) standardized diagnostic criteria proposed by the Radiological Society of North America in coronavirus disease 2019 (COVID-19) compared with reverse transcription–polymerase chain reaction (RT-PCR). Methods Seventy-one patients who underwent RT-PCR test for COVID-19 and chest CT within an interval of 4 days or less were included. Seventy-five CTs were reviewed and classified as typical, indeterminate, or atypical appearance or negative for pneumonia by 2 radiologists. With RT-PCR as reference standard, the performance of the CT diagnostic criteria in diagnosing COVID-19 was assessed. Results The prevalence of positive RT-PCR was 45.1%. It was obtained a sensitivity of 83% (95% confidence interval [CI], 78%–89%), a specificity of 97% (95% CI, 92%–99%), an accuracy of 91% (95% CI, 85%–96%), a positive predictive value of 97% (95% CI, 91%–99%), and a negative predictive value of 86% (95% CI, 80%–92%). The diagnostic performance was excellent, considering the area under the curve of 0.92 (95% CI, 0.84–0.99). Conclusions Chest CT standardized diagnostic criteria had high specificity and positive predictive value for the diagnosis of COVID-19 when presenting a typical appearance.

Journal

Journal of Computer Assisted Tomography – Wolters Kluwer Health

Published: Apr 1, 177

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