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In Utero Diffusion MRI: Challenges, Advances, and Applications

In Utero Diffusion MRI: Challenges, Advances, and Applications Downloaded from http://journals.lww.com/topicsinmri by BhDMf5ePHKbH4TTImqenVA+lpWIIBvonhQl60EtgtdlLYrLzSPu+hQedJnbNaXBf on 01/28/2021 REVIEW ARTICLE In Utero Diffusion MRI Challenges, Advances, and Applications y z y Daan Christiaens, PhD, Paddy J. Slator, PhD, Lucilio Cordero-Grande, PhD, y y z Anthony N. Price, PhD, Maria Deprez, PhD, Daniel C. Alexander, PhD, y y y Mary Rutherford, PhD, Joseph V. Hajnal, PhD, and Jana Hutter, PhD insights, but comes with specific challenges. dMRI exploits the Abstract: In utero diffusion magnetic resonance imaging (MRI) provides random motion of water, and specifically its hindrance by the unique opportunities to noninvasively study the microstructure of tissue surrounding cell membranes, to probe the tissue microarchitecture during fetal development. A wide range of developmental processes, such and thus to allow insights into tissue microstructure. Diffusion- as the growth of white matter tracts in the brain, the maturation of placental encoding gradients are employed, which can be varied in strength villous trees, or the fibers in the fetal heart remain to be studied and and timing to set sensitivity (b-value) and direction (b-vector). The b- understood in detail. Advances in fetal interventions and surgery furthermore value gives rise to different degrees of attenuation and thus informs increase the need for ever more precise http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Topics in Magnetic Resonance Imaging Wolters Kluwer Health

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References (71)

Publisher
Wolters Kluwer Health
Copyright
Copyright © 2019 Wolters Kluwer Health, Inc. All rights reserved.
ISSN
0899-3459
eISSN
1536-1004
DOI
10.1097/RMR.0000000000000211
Publisher site
See Article on Publisher Site

Abstract

Downloaded from http://journals.lww.com/topicsinmri by BhDMf5ePHKbH4TTImqenVA+lpWIIBvonhQl60EtgtdlLYrLzSPu+hQedJnbNaXBf on 01/28/2021 REVIEW ARTICLE In Utero Diffusion MRI Challenges, Advances, and Applications y z y Daan Christiaens, PhD, Paddy J. Slator, PhD, Lucilio Cordero-Grande, PhD, y y z Anthony N. Price, PhD, Maria Deprez, PhD, Daniel C. Alexander, PhD, y y y Mary Rutherford, PhD, Joseph V. Hajnal, PhD, and Jana Hutter, PhD insights, but comes with specific challenges. dMRI exploits the Abstract: In utero diffusion magnetic resonance imaging (MRI) provides random motion of water, and specifically its hindrance by the unique opportunities to noninvasively study the microstructure of tissue surrounding cell membranes, to probe the tissue microarchitecture during fetal development. A wide range of developmental processes, such and thus to allow insights into tissue microstructure. Diffusion- as the growth of white matter tracts in the brain, the maturation of placental encoding gradients are employed, which can be varied in strength villous trees, or the fibers in the fetal heart remain to be studied and and timing to set sensitivity (b-value) and direction (b-vector). The b- understood in detail. Advances in fetal interventions and surgery furthermore value gives rise to different degrees of attenuation and thus informs increase the need for ever more precise

Journal

Topics in Magnetic Resonance ImagingWolters Kluwer Health

Published: Oct 1, 2019

Keywords: brain,diffusion,fetal,in-utero,microstructure,MRI,placenta

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