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Immunotherapy: an option in the management of occupational asthma? Joaquı ´n Sastre and Santiago Quirce Purpose of review Introduction To review clinical data on immunotherapy applied to Allergen immunotherapy consists of administering gradu- occupational asthma. ally increasing quantities of an allergen extract to an Recent findings allergic patient to ameliorate the symptoms associated There are very few studies on immunotherapy in with subsequent exposure to the causative allergen [1]. occupational asthma. The best documented use of This form of treatment may be considered an immune immunotherapy in this disorder corresponds to latex allergy modifier. The most common route of administration is by among healthcare workers. There are anecdotic reports of subcutaneous injection, but in the last decade the sub- non-well controlled studies using immunotherapy with lingual route has been used as well, mainly in Europe. Its wheat flour, African maple wood, sea squirt and rat efficacy, when administered at appropriate doses, has been epithelium extracts. Subcutaneous immunotherapy with demonstrated in allergic rhinitis and asthma due to house natural rubber latex extract, at adequate doses, seems to be dust mites, pollen, some molds and some animal danders, a useful treatment in reducing cutaneous and respiratory as well as for hymenoptera
Current Opinion in Allergy and Clinical Immunology – Wolters Kluwer Health
Published: Apr 1, 2006
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