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Editorial Imaging Coronary Artery Histology A Virtual Pursuit? E. Murat Tuzcu, MD; Neil J. Weissman, MD or years, patients have been under the misconception that an algorithm with known plaque types, unknown components Fa coronary intervention of a coronary stenosis was of a human atheroma can be identified. A similar method “preventing an impending heart attack.” As cardiologists, we that also uses the radiofrequency signal from known mor- know better. In stable coronary artery disease, when we phologies to classify new signals has recently been intro- perform a coronary intervention, we do not know if the target duced by Boston Scientific Corporation (Maple Grove, Minn) site is going to evolve into a ruptured plaque and result in and is called iMap technology. acute coronary syndrome. Prediction and prevention of an All 3 IVUS plaque characterization techniques (integrated acute coronary syndrome is what the patient wants and what backscatter–IVUS, VH-IVUS, and iMap) have undergone we have been striving for years but with much frustration. We pathological validation, and all have now been applied know the characteristics of a vulnerable plaque (a large clinically. Although all 3 are commercially available some- plaque burden with positive remodeling, a large lipid core where
Circulation: Cardiovascular Imaging – Wolters Kluwer Health
Published: Jul 1, 2010
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