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Human Apolipoprotein A‐I‐C‐III Gene Complex is Located on Chromosome II

Human Apolipoprotein A‐I‐C‐III Gene Complex is Located on Chromosome II The genes for two of the apolipoproteins, apo A-I and apo C-III, previously shown to be within 3kb In the genome, were localized to human chromosome 11 by Southern blot analysis of DNA from human-rodent somatic cell hybrids. These two genes were shown to exhibit polymorphisms associated with dysllpoproteinemia and premature atherosclerosis, and It will now be possible to examine the relationship of these genes to the many others that have been assigned to this chromosome. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Arteriosclerosis Wolters Kluwer Health

Human Apolipoprotein A‐I‐C‐III Gene Complex is Located on Chromosome II

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Copyright
© 1984 by American Heart Association, Inc.
ISSN
0276-5047

Abstract

The genes for two of the apolipoproteins, apo A-I and apo C-III, previously shown to be within 3kb In the genome, were localized to human chromosome 11 by Southern blot analysis of DNA from human-rodent somatic cell hybrids. These two genes were shown to exhibit polymorphisms associated with dysllpoproteinemia and premature atherosclerosis, and It will now be possible to examine the relationship of these genes to the many others that have been assigned to this chromosome.

Journal

ArteriosclerosisWolters Kluwer Health

Published: Mar 1, 1984

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