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Host factors associated with outcome from primary human immunodeficiency virus-1 infection a b Amalio Telenti and Mary Carrington Institute of Microbiology, University Hospital Center Purpose of review and University of Lausanne, 1011 Lausanne, b The early events in human immunodeficiency virus-1 infection are increasingly Switzerland and Cancer and Inflammation Program, Laboratory of Experiment Immunology, SAIC- recognized as critical for the overall evolution of the disease. Viral and host factors Frederick, Inc., NCI-Frederick, Frederick, Maryland interact to establish a point of equilibrium defined by the viral set point. This review 21702, USA highlights new opportunities in the understanding of the genetic and genomic Correspondence to Amalio Telenti, Institute of determinants of those early events. Microbiology, University of Lausanne, 1011 Lausanne, Switzerland Recent findings Tel: +41 21 314 0550; fax: +41 21 314 4095; The field of human immunodeficiency virus host genetics is shifting from the measure of e-mail: amalio.telenti@chuv.ch long-term consequences of infection to the analysis of quantitative biological endpoints of viral control, with particular attention on the earliest events as study phenotypes. The Mary Carrington, SAIC Frederick, Building 560, Room 21-89, NCI-Frederick, Frederick, Maryland 21702, field has also been enriched by a better understanding of the determinant and complex
Current Opinion in HIV and Aids – Wolters Kluwer Health
Published: Jan 1, 2008
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