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Histologic Variants of Seminoma Mimicking Lymphatic Malignancies of the Testis A Literature Review With a Report of Case Series Focusing on Problems in Differential Diagnosis

Histologic Variants of Seminoma Mimicking Lymphatic Malignancies of the Testis A Literature... REVIEW ARTICLE Histologic Variants of Seminoma Mimicking Lymphatic Malignancies of the Testis: A Literature Review With a Report of Case Series Focusing on Problems in Differential Diagnosis Maria Rosaria Raspollini, MD, PhD treatment after surgery. In addition, in some cases, the Abstract: We focused on the clinical and morphologic sim- differential diagnosis between the histologic variants of ilarities that may cause a misdiagnosis between histologic var- seminoma and lymphatic malignances of the testis is not iants of seminoma and we highlighted the differences between easy and is often misleading. spermatocytic seminoma and high–mitotic rate seminoma or Pathologists frequently deal with testicular masses, plasmocytic testicular lymphoma or plasmacytoma of the testis. particularly in frozen sections, where the morphologic We emphasized on the difficult points in the differential diag- details are less defined, and they are required to confirm nosis, with a critical review of the literature, reporting a case or rule out a malignancy. series to discuss problems in differential diagnosis. Herein, we focus on morphologic similarities that may cause a misdiagnosis between the histologic variants Key Words: testis, seminoma, spermatocytic seminoma, lym- of seminoma, and we highlight the differences between phoma, plasmacytoma spermatocytic seminoma and high–mitotic rate seminoma (Appl http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Applied Immunohistochemistry & Molecular Morphology Wolters Kluwer Health

Histologic Variants of Seminoma Mimicking Lymphatic Malignancies of the Testis A Literature Review With a Report of Case Series Focusing on Problems in Differential Diagnosis

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Copyright
Copyright © 2013 by Lippincott Williams & Wilkins
ISSN
1541-2016
DOI
10.1097/PAI.0b013e3182927317
pmid
23958546
Publisher site
See Article on Publisher Site

Abstract

REVIEW ARTICLE Histologic Variants of Seminoma Mimicking Lymphatic Malignancies of the Testis: A Literature Review With a Report of Case Series Focusing on Problems in Differential Diagnosis Maria Rosaria Raspollini, MD, PhD treatment after surgery. In addition, in some cases, the Abstract: We focused on the clinical and morphologic sim- differential diagnosis between the histologic variants of ilarities that may cause a misdiagnosis between histologic var- seminoma and lymphatic malignances of the testis is not iants of seminoma and we highlighted the differences between easy and is often misleading. spermatocytic seminoma and high–mitotic rate seminoma or Pathologists frequently deal with testicular masses, plasmocytic testicular lymphoma or plasmacytoma of the testis. particularly in frozen sections, where the morphologic We emphasized on the difficult points in the differential diag- details are less defined, and they are required to confirm nosis, with a critical review of the literature, reporting a case or rule out a malignancy. series to discuss problems in differential diagnosis. Herein, we focus on morphologic similarities that may cause a misdiagnosis between the histologic variants Key Words: testis, seminoma, spermatocytic seminoma, lym- of seminoma, and we highlight the differences between phoma, plasmacytoma spermatocytic seminoma and high–mitotic rate seminoma (Appl

Journal

Applied Immunohistochemistry & Molecular MorphologyWolters Kluwer Health

Published: May 1, 2014

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