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High-Risk Plaque Regression and Stabilization

High-Risk Plaque Regression and Stabilization Circulation: Cardiovascular Imaging CARDIOVASCULAR IMAGES High-Risk Plaque Regression and Stabilization Hybrid Noninvasive Morphological and Hemodynamic Assessment oronary computed tomography angiography (CCTA) holds a prime role in Andreas A. Giannopoulos, noninvasive assessment of atherosclerosis by enabling plaque characteriza- MD, PhD Ction and serial imaging. The napkin-ring sign has been described in plaques Dimitrios Mitsouras, PhD that are characterized at CCTA by a low attenuation center, covered by a higher Andrea Bartykowszki, MD attenuation ring-like periphery. Such atherosclerotic plaques are closely linked with Béla Merkely, MD, PhD, future acute coronary syndromes, independent of other high-risk CCTA plaque DSc features, such as low attenuation plaque and positive remodeling. Medical treat- Yiannis S. Chatzizisis, MD, ment, primarily with the use of statins, that promote plaque stabilization, has been PhD associated with resolution of inflammation and favorable histological changes in Ronny R. Buechel, MD coronary plaques, leading to plaque regression. Philipp A. Kaufmann, MD We present a 62-year-old male patient with history of hypertension and dyslip- Oliver Gaemperli, MD idemia who was assessed with CCTA because of atypical chest pain (Figure 1). A Pál Maurovich-Horvat, high-risk coronary plaque was identified at the mid left anterior descending artery MD, PhD, MPH (LAD) resulting in moderate luminal http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Circulation: Cardiovascular Imaging Wolters Kluwer Health

High-Risk Plaque Regression and Stabilization

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References (6)

Publisher
Wolters Kluwer Health
Copyright
© 2018 American Heart Association, Inc.
ISSN
1941-9651
eISSN
1942-0080
DOI
10.1161/CIRCIMAGING.118.007888
Publisher site
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Abstract

Circulation: Cardiovascular Imaging CARDIOVASCULAR IMAGES High-Risk Plaque Regression and Stabilization Hybrid Noninvasive Morphological and Hemodynamic Assessment oronary computed tomography angiography (CCTA) holds a prime role in Andreas A. Giannopoulos, noninvasive assessment of atherosclerosis by enabling plaque characteriza- MD, PhD Ction and serial imaging. The napkin-ring sign has been described in plaques Dimitrios Mitsouras, PhD that are characterized at CCTA by a low attenuation center, covered by a higher Andrea Bartykowszki, MD attenuation ring-like periphery. Such atherosclerotic plaques are closely linked with Béla Merkely, MD, PhD, future acute coronary syndromes, independent of other high-risk CCTA plaque DSc features, such as low attenuation plaque and positive remodeling. Medical treat- Yiannis S. Chatzizisis, MD, ment, primarily with the use of statins, that promote plaque stabilization, has been PhD associated with resolution of inflammation and favorable histological changes in Ronny R. Buechel, MD coronary plaques, leading to plaque regression. Philipp A. Kaufmann, MD We present a 62-year-old male patient with history of hypertension and dyslip- Oliver Gaemperli, MD idemia who was assessed with CCTA because of atypical chest pain (Figure 1). A Pál Maurovich-Horvat, high-risk coronary plaque was identified at the mid left anterior descending artery MD, PhD, MPH (LAD) resulting in moderate luminal

Journal

Circulation: Cardiovascular Imaging – Wolters Kluwer Health

Published: Jul 1, 2018

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