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High-Risk Coronary Plaque on Computed Tomography Angiography

High-Risk Coronary Plaque on Computed Tomography Angiography Editorial High-Risk Coronary Plaque on Computed Tomography Angiography Time to Recognize a New Imaging Risk Factor Maros Ferencik, MD, PhD, MCR; Udo Hoffmann, MD, MPH oronary computed tomography angiography (CTA) is 2.3-fold increase of MACE, respectively. An often-used posi- Cthe only noninvasive imaging technique that reliably tivity criterion requiring the presence of at least 2 high-risk depicts the anatomic extent of coronary artery disease (CAD). plaque features was associated with 9-fold increase of MACE. Specifically, the analysis of ECG-synchronized coronary CTA The strengths of the study are well-described and stan- images permits accurate assessment of both the presence and dardized analytical methods, large population size, appropri- degree of luminal obstruction and the presence, morphology, ate follow-up, and inclusion of both traditional assessment for and composition of coronary atherosclerosis, including high- calcified and noncalcified plaque and high-risk plaque fea- risk plaque features, such as positive remodeling, low com- tures. Important limitations of the analysis include the lack puted tomography attenuation plaque, napkin-ring sign, and of reporting absolute event rates and multivariable-adjusted 1–6 spotty calcium. Although it is well established that patients hazard ratios for high-risk plaque and the lack of adjusting the with significant luminal obstruction diagnosed by coronary prognostic http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Circulation: Cardiovascular Imaging Wolters Kluwer Health

High-Risk Coronary Plaque on Computed Tomography Angiography

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Publisher
Wolters Kluwer Health
Copyright
© 2018 American Heart Association, Inc.
ISSN
1941-9651
eISSN
1942-0080
DOI
10.1161/CIRCIMAGING.117.007288
Publisher site
See Article on Publisher Site

Abstract

Editorial High-Risk Coronary Plaque on Computed Tomography Angiography Time to Recognize a New Imaging Risk Factor Maros Ferencik, MD, PhD, MCR; Udo Hoffmann, MD, MPH oronary computed tomography angiography (CTA) is 2.3-fold increase of MACE, respectively. An often-used posi- Cthe only noninvasive imaging technique that reliably tivity criterion requiring the presence of at least 2 high-risk depicts the anatomic extent of coronary artery disease (CAD). plaque features was associated with 9-fold increase of MACE. Specifically, the analysis of ECG-synchronized coronary CTA The strengths of the study are well-described and stan- images permits accurate assessment of both the presence and dardized analytical methods, large population size, appropri- degree of luminal obstruction and the presence, morphology, ate follow-up, and inclusion of both traditional assessment for and composition of coronary atherosclerosis, including high- calcified and noncalcified plaque and high-risk plaque fea- risk plaque features, such as positive remodeling, low com- tures. Important limitations of the analysis include the lack puted tomography attenuation plaque, napkin-ring sign, and of reporting absolute event rates and multivariable-adjusted 1–6 spotty calcium. Although it is well established that patients hazard ratios for high-risk plaque and the lack of adjusting the with significant luminal obstruction diagnosed by coronary prognostic

Journal

Circulation: Cardiovascular Imaging – Wolters Kluwer Health

Published: Jan 1, 2018

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