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LETTER TO THE EDITOR umnar cells with supranuclear mucin, observed at the LD subserosal level. Heterogeneity of which was positive for Alcian blue. Although the morphologic features These structures were not connected of this presented case did not suggest Luschka Ducts of the to mucosa. At distance, on another a malignant tumor, the heterogenous Gallbladder slide, there was a 2.5 mm rim of hep- morphophenotype and immuno- atocytes (1 to 8 hepatocytes in height) phenotype of such lesions should be and a detached fragment of 1 mm that acknowledged as it might be relevant To the Editor: did not show a biliary structure in the differential diagnosis with well- The Luschka ducts (LDs) are (the resected specimen was analyzed differentiated adenocarcinomas, includ- well-known structures that were de- entirely microscopically). Immuno- ing biliary or pancreatic carcinomas. scribed in the 19th century, around the histochemical analysis revealed that start of the microscope era. However, Adriana Handra-Luca, MD, PhD*w the epithelial cells of LDs expressed the recent review of Schnelldorfer et al Seung-Mo Hong, MD, PhDz cytokeratins 7 (membrane and/or cy- suggests that information on the histo- *Service d’Anatomie pathologique toplasmic), 19 (membrane and/or cy- logic descriptions are limited. In addi- APHP
Applied Immunohistochemistry & Molecular Morphology – Wolters Kluwer Health
Published: Oct 1, 2014
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